YIPF4 protein (Homo sapiens) - STRING network view

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Score

YIPF4

Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure (244 aa)

Predicted Functional Partners:

YIPF3

0.985

UBC

0.893

YIF1B

0.801

GTF3A

0.775

YIF1A

0.768

YIPF2

0.720

YIPF1

0.720

SUFU

0.508

RNF185

0.499

CCR6

0.497

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCR6	YIPF4	ENSP00000339393	ENSP00000238831	chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level	Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure	0.497
GTF3A	YIF1A	ENSP00000370532	ENSP00000366098	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi	0.586
GTF3A	YIF1B	ENSP00000370532	ENSP00000343435	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 interacting factor homolog B (S. cerevisiae)	0.623
GTF3A	YIPF1	ENSP00000370532	ENSP00000072644	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 domain family, member 1	0.502
GTF3A	YIPF2	ENSP00000370532	ENSP00000253031	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 domain family, member 2	0.507
GTF3A	YIPF3	ENSP00000370532	ENSP00000361499	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 domain family, member 3; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis	0.623
GTF3A	YIPF4	ENSP00000370532	ENSP00000238831	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure	0.775
RNF185	UBC	ENSP00000320508	ENSP00000344818	ring finger protein 185; Mitochondrial E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating ’Lys-63’-linked polyubiquitination of BNIP1	ubiquitin C	0.977
RNF185	YIPF2	ENSP00000320508	ENSP00000253031	ring finger protein 185; Mitochondrial E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating ’Lys-63’-linked polyubiquitination of BNIP1	Yip1 domain family, member 2	0.648
RNF185	YIPF4	ENSP00000320508	ENSP00000238831	ring finger protein 185; Mitochondrial E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating ’Lys-63’-linked polyubiquitination of BNIP1	Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure	0.499
SUFU	UBC	ENSP00000358918	ENSP00000344818	suppressor of fused homolog (Drosophila); Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full len [...]	ubiquitin C	0.620
SUFU	YIPF4	ENSP00000358918	ENSP00000238831	suppressor of fused homolog (Drosophila); Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full len [...]	Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure	0.508
UBC	RNF185	ENSP00000344818	ENSP00000320508	ubiquitin C	ring finger protein 185; Mitochondrial E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating ’Lys-63’-linked polyubiquitination of BNIP1	0.977
UBC	SUFU	ENSP00000344818	ENSP00000358918	ubiquitin C	suppressor of fused homolog (Drosophila); Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full len [...]	0.620
UBC	YIF1A	ENSP00000344818	ENSP00000366098	ubiquitin C	Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi	0.828
UBC	YIF1B	ENSP00000344818	ENSP00000343435	ubiquitin C	Yip1 interacting factor homolog B (S. cerevisiae)	0.824
UBC	YIPF1	ENSP00000344818	ENSP00000072644	ubiquitin C	Yip1 domain family, member 1	0.620
UBC	YIPF3	ENSP00000344818	ENSP00000361499	ubiquitin C	Yip1 domain family, member 3; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis	0.854
UBC	YIPF4	ENSP00000344818	ENSP00000238831	ubiquitin C	Yip1 domain family, member 4; Involved in the maintenance of the Golgi structure	0.893
YIF1A	GTF3A	ENSP00000366098	ENSP00000370532	Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi	general transcription factor IIIA; Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA’s. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes	0.586

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