node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LMOD1 | MYLK | ENSP00000356257 | ENSP00000353452 | leiomodin 1 (smooth muscle) | myosin light chain kinase | 0.914 |
LMOD1 | PXN | ENSP00000356257 | ENSP00000228307 | leiomodin 1 (smooth muscle) | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | 0.903 |
LMOD1 | SORBS1 | ENSP00000356257 | ENSP00000355136 | leiomodin 1 (smooth muscle) | sorbin and SH3 domain containing 1 | 0.900 |
LMOD1 | SORBS3 | ENSP00000356257 | ENSP00000240123 | leiomodin 1 (smooth muscle) | sorbin and SH3 domain containing 3; Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain | 0.902 |
LMOD1 | TLN1 | ENSP00000356257 | ENSP00000316029 | leiomodin 1 (smooth muscle) | talin 1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity) | 0.900 |
LMOD1 | VCL | ENSP00000356257 | ENSP00000211998 | leiomodin 1 (smooth muscle) | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | 0.903 |
MYLK | LMOD1 | ENSP00000353452 | ENSP00000356257 | myosin light chain kinase | leiomodin 1 (smooth muscle) | 0.914 |
MYLK | PXN | ENSP00000353452 | ENSP00000228307 | myosin light chain kinase | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | 0.965 |
MYLK | RTKN | ENSP00000353452 | ENSP00000272430 | myosin light chain kinase | rhotekin; Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures | 0.511 |
MYLK | SORBS1 | ENSP00000353452 | ENSP00000355136 | myosin light chain kinase | sorbin and SH3 domain containing 1 | 0.902 |
MYLK | SORBS3 | ENSP00000353452 | ENSP00000240123 | myosin light chain kinase | sorbin and SH3 domain containing 3; Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain | 0.915 |
MYLK | TLN1 | ENSP00000353452 | ENSP00000316029 | myosin light chain kinase | talin 1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity) | 0.919 |
MYLK | VCL | ENSP00000353452 | ENSP00000211998 | myosin light chain kinase | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | 0.965 |
PXN | LMOD1 | ENSP00000228307 | ENSP00000356257 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | leiomodin 1 (smooth muscle) | 0.903 |
PXN | MYLK | ENSP00000228307 | ENSP00000353452 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | myosin light chain kinase | 0.965 |
PXN | RTKN | ENSP00000228307 | ENSP00000272430 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | rhotekin; Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures | 0.580 |
PXN | SORBS1 | ENSP00000228307 | ENSP00000355136 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | sorbin and SH3 domain containing 1 | 0.970 |
PXN | SORBS3 | ENSP00000228307 | ENSP00000240123 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | sorbin and SH3 domain containing 3; Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain | 0.945 |
PXN | TLN1 | ENSP00000228307 | ENSP00000316029 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | talin 1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity) | 0.998 |
PXN | VCL | ENSP00000228307 | ENSP00000211998 | paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) | vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion | 0.999 |