PYROXD1 protein (Homo sapiens) - STRING network view

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PYROXD1

pyridine nucleotide-disulphide oxidoreductase domain 1 (500 aa)

Predicted Functional Partners:

UPRT

0.929

LSM4

0.896

DCAF8L2

0.700

ILF2

0.644

CCDC58

0.640

UBC

0.620

ILF3

0.543

MCTP1

0.459

CAPZA3

0.416

ZBED4

0.412

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPZA3	PYROXD1	ENSP00000326238	ENSP00000240651	capping protein (actin filament) muscle Z-line, alpha 3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity)	pyridine nucleotide-disulphide oxidoreductase domain 1	0.416
CCDC58	PYROXD1	ENSP00000291458	ENSP00000240651	coiled-coil domain containing 58	pyridine nucleotide-disulphide oxidoreductase domain 1	0.640
CCDC58	UBC	ENSP00000291458	ENSP00000344818	coiled-coil domain containing 58	ubiquitin C	0.795
DCAF8L2	MCTP1	ENSP00000462745	ENSP00000424126	DDB1 and CUL4 associated factor 8-like 2	multiple C2 domains, transmembrane 1	0.471
DCAF8L2	PYROXD1	ENSP00000462745	ENSP00000240651	DDB1 and CUL4 associated factor 8-like 2	pyridine nucleotide-disulphide oxidoreductase domain 1	0.700
ILF2	ILF3	ENSP00000355011	ENSP00000404121	interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus	interleukin enhancer binding factor 3, 90kDa	0.993
ILF2	PYROXD1	ENSP00000355011	ENSP00000240651	interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus	pyridine nucleotide-disulphide oxidoreductase domain 1	0.644
ILF2	UBC	ENSP00000355011	ENSP00000344818	interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus	ubiquitin C	0.992
ILF3	ILF2	ENSP00000404121	ENSP00000355011	interleukin enhancer binding factor 3, 90kDa	interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus	0.993
ILF3	PYROXD1	ENSP00000404121	ENSP00000240651	interleukin enhancer binding factor 3, 90kDa	pyridine nucleotide-disulphide oxidoreductase domain 1	0.543
ILF3	UBC	ENSP00000404121	ENSP00000344818	interleukin enhancer binding factor 3, 90kDa	ubiquitin C	0.969
LSM4	PYROXD1	ENSP00000469468	ENSP00000240651	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA	pyridine nucleotide-disulphide oxidoreductase domain 1	0.896
LSM4	UBC	ENSP00000469468	ENSP00000344818	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA	ubiquitin C	0.721
MCTP1	DCAF8L2	ENSP00000424126	ENSP00000462745	multiple C2 domains, transmembrane 1	DDB1 and CUL4 associated factor 8-like 2	0.471
MCTP1	PYROXD1	ENSP00000424126	ENSP00000240651	multiple C2 domains, transmembrane 1	pyridine nucleotide-disulphide oxidoreductase domain 1	0.459
PYROXD1	CAPZA3	ENSP00000240651	ENSP00000326238	pyridine nucleotide-disulphide oxidoreductase domain 1	capping protein (actin filament) muscle Z-line, alpha 3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity)	0.416
PYROXD1	CCDC58	ENSP00000240651	ENSP00000291458	pyridine nucleotide-disulphide oxidoreductase domain 1	coiled-coil domain containing 58	0.640
PYROXD1	DCAF8L2	ENSP00000240651	ENSP00000462745	pyridine nucleotide-disulphide oxidoreductase domain 1	DDB1 and CUL4 associated factor 8-like 2	0.700
PYROXD1	ILF2	ENSP00000240651	ENSP00000355011	pyridine nucleotide-disulphide oxidoreductase domain 1	interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus	0.644
PYROXD1	ILF3	ENSP00000240651	ENSP00000404121	pyridine nucleotide-disulphide oxidoreductase domain 1	interleukin enhancer binding factor 3, 90kDa	0.543

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