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CADPS2 CADPS2 NRDE2 NRDE2 FDFT1 FDFT1 CNTNAP5 CNTNAP5 SLITRK4 SLITRK4 CSMD2 CSMD2 DGKH DGKH SKAP2 SKAP2 KDELC2 KDELC2 PER1 PER1 ZNF804A ZNF804A
"CSMD2" - CUB and Sushi multiple domains 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSMD2CUB and Sushi multiple domains 2 (3487 aa)    
Predicted Functional Partners:
CNTNAP5
contactin associated protein-like 5; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication (1306 aa)
            score_image   0.561
SKAP2
src kinase associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway (359 aa)
            score_image   0.526
PER1
period homolog 1 (Drosophila); Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Can bind heme (By similarity) (1290 aa)
            score_image   0.525
FDFT1
farnesyl-diphosphate farnesyltransferase 1 (417 aa)
            score_image   0.501
ZNF804A
zinc finger protein 804A (1209 aa)
            score_image   0.432
DGKH
diacylglycerol kinase, eta (1220 aa)
            score_image   0.422
SLITRK4
SLIT and NTRK-like family, member 4; Suppresses neurite outgrowth (By similarity) (837 aa)
            score_image   0.422
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2 (507 aa)
            score_image   0.418
NRDE2
NRDE-2, necessary for RNA interference, domain containing (1164 aa)
            score_image   0.416
CADPS2
Ca++-dependent secretion activator 2 (1296 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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