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MTERFD3 MTERFD3 TFB1M TFB1M NSUN4 NSUN4 MTERF MTERF MALSU1 MALSU1 NSUN5 NSUN5 MTERFD2 MTERFD2 FTSJ2 FTSJ2 UBC UBC GAL3ST2 GAL3ST2 ANKMY1 ANKMY1
"MTERFD2" - MTERF domain containing 2 in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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protein homology
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MTERFD2MTERF domain containing 2; Required for the targeting of the methyltransferase NSUN4 to mitochondrial large ribosomal subunit and efficient rRNA methylation (381 aa)    
Predicted Functional Partners:
NSUN4
NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis (384 aa)
        score_image   score_image   0.997
MTERF
mitochondrial transcription termination factor; Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity (399 aa)
            score_image   0.648
MTERFD3
MTERF domain containing 3; Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function (By similarity) (385 aa)
            score_image   0.636
NSUN5
NOP2/Sun domain family, member 5 (470 aa)
            score_image   0.537
GAL3ST2
galactose-3-O-sulfotransferase 2; Transfers a sulfate group to the hydroxyl group at C3 of non-reducing beta-galactosyl residues. Acts both on type 1 (Gal- beta-1,3-GlcNAc) and type 2 (Gal-beta-1,4-GlcNAc) chains with similar efficiency (398 aa)
            score_image   0.535
MALSU1
mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (234 aa)
            score_image   0.511
FTSJ2
FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase (246 aa)
            score_image   0.502
UBC
ubiquitin C (685 aa)
        score_image       0.487
ANKMY1
ankyrin repeat and MYND domain containing 1 (941 aa)
            score_image   0.459
TFB1M
transcription factor B1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (346 aa)
            score_image   0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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