FTSJ2 protein (Homo sapiens) - STRING network view

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Score

FTSJ2

FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase (246 aa)

Predicted Functional Partners:

TFB2M

0.918

TFB1M

0.917

MRM1

0.870

GTPBP4

0.786

DDX54

0.771

POLRMT

0.762

BYSL

0.754

YME1L1

0.739

NSUN4

0.734

EBNA1BP2

0.711

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BYSL	DDX54	ENSP00000230340	ENSP00000323858	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	0.873
BYSL	EBNA1BP2	ENSP00000230340	ENSP00000407323	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	0.942
BYSL	FTSJ2	ENSP00000230340	ENSP00000242257	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase	0.754
BYSL	GTPBP4	ENSP00000230340	ENSP00000354040	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity)	0.930
BYSL	NSUN4	ENSP00000230340	ENSP00000419740	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis	0.493
BYSL	TFB1M	ENSP00000230340	ENSP00000356134	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	transcription factor B1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity	0.958
BYSL	TFB2M	ENSP00000230340	ENSP00000355471	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	transcription factor B2, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity	0.983
DDX54	BYSL	ENSP00000323858	ENSP00000230340	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	0.873
DDX54	EBNA1BP2	ENSP00000323858	ENSP00000407323	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	0.990
DDX54	FTSJ2	ENSP00000323858	ENSP00000242257	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase	0.771
DDX54	GTPBP4	ENSP00000323858	ENSP00000354040	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity)	0.980
DDX54	NSUN4	ENSP00000323858	ENSP00000419740	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis	0.671
DDX54	TFB1M	ENSP00000323858	ENSP00000356134	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	transcription factor B1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity	0.665
DDX54	TFB2M	ENSP00000323858	ENSP00000355471	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	transcription factor B2, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity	0.665
EBNA1BP2	BYSL	ENSP00000407323	ENSP00000230340	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	0.942
EBNA1BP2	DDX54	ENSP00000407323	ENSP00000323858	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors	0.990
EBNA1BP2	FTSJ2	ENSP00000407323	ENSP00000242257	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase	0.711
EBNA1BP2	GTPBP4	ENSP00000407323	ENSP00000354040	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity)	0.976
EBNA1BP2	NSUN4	ENSP00000407323	ENSP00000419740	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	NOP2/Sun domain family, member 4; Involved in mitochondrial ribosome large subunit biogenesis	0.614
EBNA1BP2	TFB1M	ENSP00000407323	ENSP00000356134	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	transcription factor B1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity	0.737

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