node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14orf119 | C19orf43 | ENSP00000322238 | ENSP00000242784 | chromosome 14 open reading frame 119 | chromosome 19 open reading frame 43 | 0.414 |
C19orf43 | C14orf119 | ENSP00000242784 | ENSP00000322238 | chromosome 19 open reading frame 43 | chromosome 14 open reading frame 119 | 0.414 |
C19orf43 | DDX46 | ENSP00000242784 | ENSP00000346236 | chromosome 19 open reading frame 43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation | 0.414 |
C19orf43 | EFCAB7 | ENSP00000242784 | ENSP00000360129 | chromosome 19 open reading frame 43 | EF-hand calcium binding domain 7 | 0.472 |
C19orf43 | RPL36 | ENSP00000242784 | ENSP00000252543 | chromosome 19 open reading frame 43 | ribosomal protein L36 | 0.644 |
C19orf43 | SF3A2 | ENSP00000242784 | ENSP00000221494 | chromosome 19 open reading frame 43 | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | 0.905 |
C19orf43 | SNRPA | ENSP00000242784 | ENSP00000243563 | chromosome 19 open reading frame 43 | small nuclear ribonucleoprotein polypeptide A; Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5’-UGCAC-3’ motif in vitro | 0.961 |
C19orf43 | UBC | ENSP00000242784 | ENSP00000344818 | chromosome 19 open reading frame 43 | ubiquitin C | 0.620 |
DDX46 | C19orf43 | ENSP00000346236 | ENSP00000242784 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation | chromosome 19 open reading frame 43 | 0.414 |
DDX46 | SF3A2 | ENSP00000346236 | ENSP00000221494 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | 0.999 |
DDX46 | UBC | ENSP00000346236 | ENSP00000344818 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation | ubiquitin C | 0.795 |
EFCAB7 | C19orf43 | ENSP00000360129 | ENSP00000242784 | EF-hand calcium binding domain 7 | chromosome 19 open reading frame 43 | 0.472 |
EFCAB7 | UBC | ENSP00000360129 | ENSP00000344818 | EF-hand calcium binding domain 7 | ubiquitin C | 0.421 |
RPL36 | C19orf43 | ENSP00000252543 | ENSP00000242784 | ribosomal protein L36 | chromosome 19 open reading frame 43 | 0.644 |
RPL36 | UBC | ENSP00000252543 | ENSP00000344818 | ribosomal protein L36 | ubiquitin C | 0.958 |
SF3A2 | C19orf43 | ENSP00000221494 | ENSP00000242784 | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | chromosome 19 open reading frame 43 | 0.905 |
SF3A2 | DDX46 | ENSP00000221494 | ENSP00000346236 | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; Plays an essential role in splicing, either prior to, or during splicing A complex formation | 0.999 |
SF3A2 | SNRPA | ENSP00000221494 | ENSP00000243563 | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | small nuclear ribonucleoprotein polypeptide A; Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5’-UGCAC-3’ motif in vitro | 0.991 |
SF3A2 | UBC | ENSP00000221494 | ENSP00000344818 | splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex | ubiquitin C | 0.800 |
SNRPA | C19orf43 | ENSP00000243563 | ENSP00000242784 | small nuclear ribonucleoprotein polypeptide A; Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5’-UGCAC-3’ motif in vitro | chromosome 19 open reading frame 43 | 0.961 |