node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY6 | ATP1B3 | ENSP00000311405 | ENSP00000286371 | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | 0.752 |
ADCY6 | MITF | ENSP00000311405 | ENSP00000295600 | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | microphthalmia-associated transcription factor | 0.499 |
ADCY6 | PAIP2B | ENSP00000311405 | ENSP00000244221 | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | poly(A) binding protein interacting protein 2B | 0.753 |
ADCY6 | SLC1A1 | ENSP00000311405 | ENSP00000262352 | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity) | 0.688 |
ADCY6 | UBC | ENSP00000311405 | ENSP00000344818 | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | ubiquitin C | 0.518 |
ANKRD53 | PAIP2B | ENSP00000353796 | ENSP00000244221 | ankyrin repeat domain 53 | poly(A) binding protein interacting protein 2B | 0.479 |
ANKRD53 | PCOTH | ENSP00000353796 | ENSP00000396192 | ankyrin repeat domain 53 | protein PCOTH isoform 1 ; May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway | 0.625 |
ATP1B3 | ADCY6 | ENSP00000286371 | ENSP00000311405 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | 0.752 |
ATP1B3 | MITF | ENSP00000286371 | ENSP00000295600 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | microphthalmia-associated transcription factor | 0.438 |
ATP1B3 | OTX1 | ENSP00000286371 | ENSP00000282549 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | orthodenticle homeobox 1; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS)- 5’-TCTAATCCC-3’ | 0.404 |
ATP1B3 | PAIP2B | ENSP00000286371 | ENSP00000244221 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | poly(A) binding protein interacting protein 2B | 0.800 |
ATP1B3 | SLC1A1 | ENSP00000286371 | ENSP00000262352 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity) | 0.750 |
ATP1B3 | UBC | ENSP00000286371 | ENSP00000344818 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | ubiquitin C | 0.943 |
MITF | ADCY6 | ENSP00000295600 | ENSP00000311405 | microphthalmia-associated transcription factor | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | 0.499 |
MITF | ATP1B3 | ENSP00000295600 | ENSP00000286371 | microphthalmia-associated transcription factor | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | 0.438 |
MITF | PAIP2B | ENSP00000295600 | ENSP00000244221 | microphthalmia-associated transcription factor | poly(A) binding protein interacting protein 2B | 0.439 |
OTX1 | ATP1B3 | ENSP00000282549 | ENSP00000286371 | orthodenticle homeobox 1; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS)- 5’-TCTAATCCC-3’ | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | 0.404 |
OTX1 | PAIP2B | ENSP00000282549 | ENSP00000244221 | orthodenticle homeobox 1; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS)- 5’-TCTAATCCC-3’ | poly(A) binding protein interacting protein 2B | 0.410 |
PABPC1 | PAIP1 | ENSP00000313007 | ENSP00000302768 | poly(A) binding protein, cytoplasmic 1; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre- mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability [...] | poly(A) binding protein interacting protein 1; Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of insta [...] | 0.999 |
PABPC1 | PAIP2B | ENSP00000313007 | ENSP00000244221 | poly(A) binding protein, cytoplasmic 1; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre- mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability [...] | poly(A) binding protein interacting protein 2B | 0.943 |