| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGR2 | DAG1 | ENSP00000391490 | ENSP00000312435 | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.849 |
| AGR2 | ESR1 | ENSP00000391490 | ENSP00000206249 | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | 0.481 |
| AGR2 | LYPD3 | ENSP00000391490 | ENSP00000244333 | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.989 |
| AGR3 | DAG1 | ENSP00000308606 | ENSP00000312435 | anterior gradient 3 homolog (Xenopus laevis) | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.802 |
| AGR3 | LYPD3 | ENSP00000308606 | ENSP00000244333 | anterior gradient 3 homolog (Xenopus laevis) | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.971 |
| CTRB1 | LYPD3 | ENSP00000354294 | ENSP00000244333 | chymotrypsinogen B1 | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.576 |
| DAG1 | AGR2 | ENSP00000312435 | ENSP00000391490 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | 0.849 |
| DAG1 | AGR3 | ENSP00000312435 | ENSP00000308606 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | anterior gradient 3 homolog (Xenopus laevis) | 0.802 |
| DAG1 | LAMB2 | ENSP00000312435 | ENSP00000307156 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | laminin, beta 2 (laminin S); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.953 |
| DAG1 | LYPD3 | ENSP00000312435 | ENSP00000244333 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.663 |
| ENSG00000196355 | LYPD3 | ENSP00000391536 | ENSP00000244333 | Uncharacterized protein | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.580 |
| ESR1 | AGR2 | ENSP00000206249 | ENSP00000391490 | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | 0.481 |
| ESR1 | LYPD3 | ENSP00000206249 | ENSP00000244333 | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial [...] | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.440 |
| LAMB2 | DAG1 | ENSP00000307156 | ENSP00000312435 | laminin, beta 2 (laminin S); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.953 |
| LAMB2 | LYPD3 | ENSP00000307156 | ENSP00000244333 | laminin, beta 2 (laminin S); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.801 |
| LGALS3 | LYPD3 | ENSP00000254301 | ENSP00000244333 | lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | 0.822 |
| LYPD3 | AGR2 | ENSP00000244333 | ENSP00000391490 | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | anterior gradient 2 homolog (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth | 0.989 |
| LYPD3 | AGR3 | ENSP00000244333 | ENSP00000308606 | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | anterior gradient 3 homolog (Xenopus laevis) | 0.971 |
| LYPD3 | CTRB1 | ENSP00000244333 | ENSP00000354294 | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | chymotrypsinogen B1 | 0.576 |
| LYPD3 | DAG1 | ENSP00000244333 | ENSP00000312435 | LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.663 |
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