node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG10 | CPNE5 | ENSP00000266483 | ENSP00000244751 | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.600 |
ALG10 | UBC | ENSP00000266483 | ENSP00000344818 | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol | ubiquitin C | 0.620 |
ALG10B | CPNE5 | ENSP00000310120 | ENSP00000244751 | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast); Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.600 |
ALG10B | UBC | ENSP00000310120 | ENSP00000344818 | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast); Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 | ubiquitin C | 0.483 |
ARHGAP44 | CPNE5 | ENSP00000368994 | ENSP00000244751 | Rho GTPase activating protein 44; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.473 |
C12orf55 | CPNE5 | ENSP00000431759 | ENSP00000244751 | chromosome 12 open reading frame 55 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.472 |
C12orf55 | TMEM156 | ENSP00000431759 | ENSP00000371364 | chromosome 12 open reading frame 55 | transmembrane protein 156 | 0.658 |
CPNE5 | ALG10 | ENSP00000244751 | ENSP00000266483 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol | 0.600 |
CPNE5 | ALG10B | ENSP00000244751 | ENSP00000310120 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast); Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 | 0.600 |
CPNE5 | ARHGAP44 | ENSP00000244751 | ENSP00000368994 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | Rho GTPase activating protein 44; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1 | 0.473 |
CPNE5 | C12orf55 | ENSP00000244751 | ENSP00000431759 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | chromosome 12 open reading frame 55 | 0.472 |
CPNE5 | HECTD2 | ENSP00000244751 | ENSP00000298068 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | HECT domain containing E3 ubiquitin protein ligase 2; Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity) | 0.493 |
CPNE5 | TCF20 | ENSP00000244751 | ENSP00000352463 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | transcription factor 20 (AR1); Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator | 0.588 |
CPNE5 | TMEM156 | ENSP00000244751 | ENSP00000371364 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | transmembrane protein 156 | 0.503 |
CPNE5 | TRANK1 | ENSP00000244751 | ENSP00000416168 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.458 |
CPNE5 | UBC | ENSP00000244751 | ENSP00000344818 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | ubiquitin C | 0.483 |
CPNE5 | VPS13A | ENSP00000244751 | ENSP00000353422 | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.552 |
HECTD2 | CPNE5 | ENSP00000298068 | ENSP00000244751 | HECT domain containing E3 ubiquitin protein ligase 2; Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity) | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.493 |
HECTD2 | UBC | ENSP00000298068 | ENSP00000344818 | HECT domain containing E3 ubiquitin protein ligase 2; Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity) | ubiquitin C | 0.609 |
TCF20 | CPNE5 | ENSP00000352463 | ENSP00000244751 | transcription factor 20 (AR1); Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator | copine V; May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity) | 0.588 |