| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDH17 | TCF15 | ENSP00000027335 | ENSP00000246080 | cadherin 17, LI cadherin (liver-intestine); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.566 |
| DYNC1I2 | TCF15 | ENSP00000380308 | ENSP00000246080 | dynein, cytoplasmic 1, intermediate chain 2 | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.583 |
| FOXC1 | LFNG | ENSP00000370256 | ENSP00000222725 | forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5’- GTAAACAAA-3’ in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | 0.418 |
| FOXC1 | TCF15 | ENSP00000370256 | ENSP00000246080 | forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5’- GTAAACAAA-3’ in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.779 |
| FOXC2 | LFNG | ENSP00000326371 | ENSP00000222725 | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | 0.487 |
| FOXC2 | PAX1 | ENSP00000326371 | ENSP00000381499 | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | paired box 1; This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity) | 0.413 |
| FOXC2 | TCF15 | ENSP00000326371 | ENSP00000246080 | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.817 |
| FOXQ1 | LFNG | ENSP00000296839 | ENSP00000222725 | forkhead box Q1; Plays a role in hair follicle differentiation (By similarity) | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | 0.408 |
| FOXQ1 | TCF15 | ENSP00000296839 | ENSP00000246080 | forkhead box Q1; Plays a role in hair follicle differentiation (By similarity) | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.579 |
| LFNG | FOXC1 | ENSP00000222725 | ENSP00000370256 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5’- GTAAACAAA-3’ in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye | 0.418 |
| LFNG | FOXC2 | ENSP00000222725 | ENSP00000326371 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | 0.487 |
| LFNG | FOXQ1 | ENSP00000222725 | ENSP00000296839 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | forkhead box Q1; Plays a role in hair follicle differentiation (By similarity) | 0.408 |
| LFNG | TCF15 | ENSP00000222725 | ENSP00000246080 | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity) | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.584 |
| MKX | TCF15 | ENSP00000364946 | ENSP00000246080 | mohawk homeobox; May act as a morphogenetic regulator of cell adhesion (By similarity) | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.767 |
| PAX1 | FOXC2 | ENSP00000381499 | ENSP00000326371 | paired box 1; This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity) | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | 0.413 |
| PAX1 | TCF15 | ENSP00000381499 | ENSP00000246080 | paired box 1; This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity) | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | 0.892 |
| TCF15 | CDH17 | ENSP00000246080 | ENSP00000027335 | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | cadherin 17, LI cadherin (liver-intestine); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport | 0.566 |
| TCF15 | DYNC1I2 | ENSP00000246080 | ENSP00000380308 | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | dynein, cytoplasmic 1, intermediate chain 2 | 0.583 |
| TCF15 | FOXC1 | ENSP00000246080 | ENSP00000370256 | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5’- GTAAACAAA-3’ in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye | 0.779 |
| TCF15 | FOXC2 | ENSP00000246080 | ENSP00000326371 | transcription factor 15 (basic helix-loop-helix); May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm | forkhead box C2 (MFH-1, mesenchyme forkhead 1); Transcriptional activator. Might be involved in the formation of special mesenchymal tissues | 0.817 |
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