node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRF1 | GTF2A2 | ENSP00000448323 | ENSP00000379372 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | 0.446 |
BRF1 | TAF1 | ENSP00000448323 | ENSP00000276072 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.770 |
BRF1 | TAF1L | ENSP00000448323 | ENSP00000418379 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | 0.737 |
BRF1 | TBPL2 | ENSP00000448323 | ENSP00000247219 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) | TATA box binding protein like 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity) | 0.991 |
BRF2 | GTF2A2 | ENSP00000220659 | ENSP00000379372 | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | 0.446 |
BRF2 | TAF1 | ENSP00000220659 | ENSP00000276072 | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.737 |
BRF2 | TAF1L | ENSP00000220659 | ENSP00000418379 | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | 0.737 |
BRF2 | TBPL2 | ENSP00000220659 | ENSP00000247219 | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites | TATA box binding protein like 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity) | 0.977 |
DR1 | GTF2B | ENSP00000359290 | ENSP00000359531 | down-regulator of transcription 1, TBP-binding (negative cofactor 2); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 | general transcription factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II | 0.847 |
DR1 | TAF1 | ENSP00000359290 | ENSP00000276072 | down-regulator of transcription 1, TBP-binding (negative cofactor 2); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.524 |
DR1 | TAF3 | ENSP00000359290 | ENSP00000340271 | down-regulator of transcription 1, TBP-binding (negative cofactor 2); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process | 0.583 |
DR1 | TBPL2 | ENSP00000359290 | ENSP00000247219 | down-regulator of transcription 1, TBP-binding (negative cofactor 2); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 | TATA box binding protein like 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity) | 0.962 |
GTF2A2 | BRF1 | ENSP00000379372 | ENSP00000448323 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) | 0.446 |
GTF2A2 | BRF2 | ENSP00000379372 | ENSP00000220659 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites | 0.446 |
GTF2A2 | GTF2B | ENSP00000379372 | ENSP00000359531 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | general transcription factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II | 0.994 |
GTF2A2 | TAF1 | ENSP00000379372 | ENSP00000276072 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.981 |
GTF2A2 | TAF1L | ENSP00000379372 | ENSP00000418379 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | 0.825 |
GTF2A2 | TAF6 | ENSP00000379372 | ENSP00000399982 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors | 0.911 |
GTF2A2 | TBPL2 | ENSP00000379372 | ENSP00000247219 | general transcription factor IIA, 2, 12kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity | TATA box binding protein like 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity) | 0.979 |
GTF2B | DR1 | ENSP00000359531 | ENSP00000359290 | general transcription factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II | down-regulator of transcription 1, TBP-binding (negative cofactor 2); The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 | 0.847 |