EVI2A protein (Homo sapiens) - STRING network view

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EVI2A

ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor (259 aa)

Predicted Functional Partners:

EVI2B

0.863

OMG

0.812

RNF135

0.688

NF1

0.661

SSH2

0.641

AK3

0.610

AK4

0.606

LRRC37B

0.510

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK3	EVI2A	ENSP00000371230	ENSP00000247270	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	0.610
AK3	EVI2B	ENSP00000371230	ENSP00000333779	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	ecotropic viral integration site 2B	0.662
AK3	OMG	ENSP00000371230	ENSP00000247271	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	oligodendrocyte myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system	0.513
AK4	EVI2A	ENSP00000322175	ENSP00000247270	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	0.606
AK4	EVI2B	ENSP00000322175	ENSP00000333779	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	ecotropic viral integration site 2B	0.610
AK4	NF1	ENSP00000322175	ENSP00000351015	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity	0.440
AK4	OMG	ENSP00000322175	ENSP00000247271	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	oligodendrocyte myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system	0.483
EVI2A	AK3	ENSP00000247270	ENSP00000371230	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	0.610
EVI2A	AK4	ENSP00000247270	ENSP00000322175	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	0.606
EVI2A	EVI2B	ENSP00000247270	ENSP00000333779	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	ecotropic viral integration site 2B	0.863
EVI2A	LRRC37B	ENSP00000247270	ENSP00000340519	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	leucine rich repeat containing 37B	0.510
EVI2A	NF1	ENSP00000247270	ENSP00000351015	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity	0.661
EVI2A	OMG	ENSP00000247270	ENSP00000247271	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	oligodendrocyte myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system	0.812
EVI2A	RNF135	ENSP00000247270	ENSP00000328340	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	ring finger protein 135; Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production	0.688
EVI2A	SSH2	ENSP00000247270	ENSP00000269033	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	slingshot homolog 2 (Drosophila); Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein	0.641
EVI2B	AK3	ENSP00000333779	ENSP00000371230	ecotropic viral integration site 2B	adenylate kinase 3; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP-AMP phosphotransferase and ITP-AMP phosphotransferase activities	0.662
EVI2B	AK4	ENSP00000333779	ENSP00000322175	ecotropic viral integration site 2B	adenylate kinase 4; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor	0.610
EVI2B	EVI2A	ENSP00000333779	ENSP00000247270	ecotropic viral integration site 2B	ecotropic viral integration site 2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor	0.863
EVI2B	LRRC37B	ENSP00000333779	ENSP00000340519	ecotropic viral integration site 2B	leucine rich repeat containing 37B	0.414
EVI2B	NF1	ENSP00000333779	ENSP00000351015	ecotropic viral integration site 2B	neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity	0.681

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