TSPAN8 protein (Homo sapiens) - STRING network view

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Score

TSPAN8

tetraspanin 8 (237 aa)

Predicted Functional Partners:

EPCAM

0.878

ITGB4

0.818

THADA

0.759

JAZF1

0.754

CDC123

0.750

CAMK1D

0.729

ADAMTS9

0.723

CDKAL1

0.659

IGF2BP2

0.658

SLC30A8

0.657

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS9	CAMK1D	ENSP00000418735	ENSP00000368124	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	0.745
ADAMTS9	CDC123	ENSP00000418735	ENSP00000281141	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	0.757
ADAMTS9	CDKAL1	ENSP00000418735	ENSP00000274695	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	CDK5 regulatory subunit associated protein 1-like 1; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine	0.659
ADAMTS9	IGF2BP2	ENSP00000418735	ENSP00000371634	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	insulin-like growth factor 2 mRNA binding protein 2; Binds to the 5’-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs	0.649
ADAMTS9	JAZF1	ENSP00000418735	ENSP00000283928	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	JAZF zinc finger 1; Potential transcription factor	0.756
ADAMTS9	SLC30A8	ENSP00000418735	ENSP00000415011	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta- cells	0.633
ADAMTS9	THADA	ENSP00000418735	ENSP00000385995	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	thyroid adenoma associated	0.765
ADAMTS9	TSPAN8	ENSP00000418735	ENSP00000247829	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	tetraspanin 8	0.723
CAMK1D	ADAMTS9	ENSP00000368124	ENSP00000418735	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	0.745
CAMK1D	CDC123	ENSP00000368124	ENSP00000281141	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	0.823
CAMK1D	CDKAL1	ENSP00000368124	ENSP00000274695	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	CDK5 regulatory subunit associated protein 1-like 1; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine	0.700
CAMK1D	IGF2BP2	ENSP00000368124	ENSP00000371634	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	insulin-like growth factor 2 mRNA binding protein 2; Binds to the 5’-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs	0.648
CAMK1D	JAZF1	ENSP00000368124	ENSP00000283928	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	JAZF zinc finger 1; Potential transcription factor	0.771
CAMK1D	SLC30A8	ENSP00000368124	ENSP00000415011	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta- cells	0.677
CAMK1D	THADA	ENSP00000368124	ENSP00000385995	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	thyroid adenoma associated	0.781
CAMK1D	TSPAN8	ENSP00000368124	ENSP00000247829	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	tetraspanin 8	0.729
CDC123	ADAMTS9	ENSP00000281141	ENSP00000418735	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican	0.757
CDC123	CAMK1D	ENSP00000281141	ENSP00000368124	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...]	0.823
CDC123	CDKAL1	ENSP00000281141	ENSP00000274695	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	CDK5 regulatory subunit associated protein 1-like 1; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine	0.721
CDC123	IGF2BP2	ENSP00000281141	ENSP00000371634	cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity)	insulin-like growth factor 2 mRNA binding protein 2; Binds to the 5’-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs	0.702

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