AAMP protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AAMP

angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway (434 aa)

Predicted Functional Partners:

WDR12

0.864

UBC

0.860

RPL10

0.796

RPL10L

0.796

RRS1

0.736

NHP2

0.736

GRWD1

0.736

BYSL

0.736

NMD3

0.735

BRIX1

0.734

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAMP	BRIX1	ENSP00000248450	ENSP00000338862	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	0.734
AAMP	BYSL	ENSP00000248450	ENSP00000230340	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	0.736
AAMP	GRWD1	ENSP00000248450	ENSP00000253237	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	glutamate-rich WD repeat containing 1	0.736
AAMP	NHP2	ENSP00000248450	ENSP00000274606	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	0.736
AAMP	NMD3	ENSP00000248450	ENSP00000307525	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	NMD3 homolog (S. cerevisiae); Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit	0.735
AAMP	RPL10	ENSP00000248450	ENSP00000341730	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	ribosomal protein L10	0.796
AAMP	RPL10L	ENSP00000248450	ENSP00000298283	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	ribosomal protein L10-like; May play a role in compensating for the inactivated X- linked gene during spermatogenesis	0.796
AAMP	RRS1	ENSP00000248450	ENSP00000322396	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity)	0.736
AAMP	UBC	ENSP00000248450	ENSP00000344818	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	ubiquitin C	0.860
AAMP	WDR12	ENSP00000248450	ENSP00000261015	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome	0.864
BRIX1	AAMP	ENSP00000338862	ENSP00000248450	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	0.734
BRIX1	BYSL	ENSP00000338862	ENSP00000230340	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	0.960
BRIX1	GRWD1	ENSP00000338862	ENSP00000253237	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	glutamate-rich WD repeat containing 1	0.984
BRIX1	NHP2	ENSP00000338862	ENSP00000274606	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	0.968
BRIX1	NMD3	ENSP00000338862	ENSP00000307525	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	NMD3 homolog (S. cerevisiae); Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit	0.898
BRIX1	RRS1	ENSP00000338862	ENSP00000322396	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity)	0.962
BRIX1	UBC	ENSP00000338862	ENSP00000344818	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	ubiquitin C	0.509
BRIX1	WDR12	ENSP00000338862	ENSP00000261015	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome	0.998
BYSL	AAMP	ENSP00000230340	ENSP00000248450	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	angio-associated, migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway	0.736
BYSL	BRIX1	ENSP00000230340	ENSP00000338862	bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit	0.960

page 1 of 5

Experiments

Cooccurrence

Textmining

Neighborhood

Coexpression

Fusion

Databases

© STRING Consortium 2017

Credits

Access

Info

About