Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DGCR6L | ENSG00000236954 | ENSP00000248879 | ENSP00000415398 | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | Uncharacterized protein | 0.507 |
| DGCR6L | PAK4 | ENSP00000248879 | ENSP00000351049 | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | p21 protein (Cdc42/Rac)-activated kinase 4; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor co [...] | 0.820 |
| DGCR6L | SLC35B3 | ENSP00000248879 | ENSP00000368981 | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon | 0.518 |
| DGCR6L | TBX1 | ENSP00000248879 | ENSP00000331791 | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.606 |
| DGCR6L | UFD1L | ENSP00000248879 | ENSP00000263202 | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.648 |
| ENSG00000236954 | DGCR6L | ENSP00000415398 | ENSP00000248879 | Uncharacterized protein | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.507 |
| PAK4 | DGCR6L | ENSP00000351049 | ENSP00000248879 | p21 protein (Cdc42/Rac)-activated kinase 4; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor co [...] | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.820 |
| SLC35B3 | DGCR6L | ENSP00000368981 | ENSP00000248879 | solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.518 |
| TBX1 | DGCR6L | ENSP00000331791 | ENSP00000248879 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.606 |
| TBX1 | UFD1L | ENSP00000331791 | ENSP00000263202 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.514 |
| UFD1L | DGCR6L | ENSP00000263202 | ENSP00000248879 | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | DiGeorge syndrome critical region gene 6-like; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.648 |
| UFD1L | TBX1 | ENSP00000263202 | ENSP00000331791 | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.514 |
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