node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA2 | SEZ6L | ENSP00000344155 | ENSP00000248933 | ATP-binding cassette, sub-family A (ABC1), member 2; Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development | seizure related 6 homolog (mouse)-like | 0.451 |
ADRBK2 | MYO18A | ENSP00000317578 | ENSP00000437073 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | myosin XVIIIA; May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration | 0.589 |
ADRBK2 | MYO18B | ENSP00000317578 | ENSP00000334563 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | myosin XVIIIB | 0.882 |
ADRBK2 | SEZ6L | ENSP00000317578 | ENSP00000248933 | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | seizure related 6 homolog (mouse)-like | 0.885 |
CHRNA10 | SEZ6L | ENSP00000250699 | ENSP00000248933 | cholinergic receptor, nicotinic, alpha 10 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and red [...] | seizure related 6 homolog (mouse)-like | 0.401 |
EFNB3 | SEZ6L | ENSP00000226091 | ENSP00000248933 | ephrin-B3; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, an [...] | seizure related 6 homolog (mouse)-like | 0.418 |
KIAA1919 | SEZ6L | ENSP00000357840 | ENSP00000248933 | KIAA1919; May function as a sodium-dependent glucose transporter (By similarity) | seizure related 6 homolog (mouse)-like | 0.642 |
MYO18A | ADRBK2 | ENSP00000437073 | ENSP00000317578 | myosin XVIIIA; May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.589 |
MYO18A | SEZ6L | ENSP00000437073 | ENSP00000248933 | myosin XVIIIA; May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration | seizure related 6 homolog (mouse)-like | 0.560 |
MYO18B | ADRBK2 | ENSP00000334563 | ENSP00000317578 | myosin XVIIIB | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.882 |
MYO18B | SEZ6L | ENSP00000334563 | ENSP00000248933 | myosin XVIIIB | seizure related 6 homolog (mouse)-like | 0.867 |
SEZ6L | ABCA2 | ENSP00000248933 | ENSP00000344155 | seizure related 6 homolog (mouse)-like | ATP-binding cassette, sub-family A (ABC1), member 2; Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development | 0.451 |
SEZ6L | ADRBK2 | ENSP00000248933 | ENSP00000317578 | seizure related 6 homolog (mouse)-like | adrenergic, beta, receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.885 |
SEZ6L | CHRNA10 | ENSP00000248933 | ENSP00000250699 | seizure related 6 homolog (mouse)-like | cholinergic receptor, nicotinic, alpha 10 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and red [...] | 0.401 |
SEZ6L | EFNB3 | ENSP00000248933 | ENSP00000226091 | seizure related 6 homolog (mouse)-like | ephrin-B3; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, an [...] | 0.418 |
SEZ6L | KIAA1919 | ENSP00000248933 | ENSP00000357840 | seizure related 6 homolog (mouse)-like | KIAA1919; May function as a sodium-dependent glucose transporter (By similarity) | 0.642 |
SEZ6L | MYO18A | ENSP00000248933 | ENSP00000437073 | seizure related 6 homolog (mouse)-like | myosin XVIIIA; May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration | 0.560 |
SEZ6L | MYO18B | ENSP00000248933 | ENSP00000334563 | seizure related 6 homolog (mouse)-like | myosin XVIIIB | 0.867 |
SEZ6L | TDRD10 | ENSP00000248933 | ENSP00000357465 | seizure related 6 homolog (mouse)-like | tudor domain containing 10 | 0.658 |
SEZ6L | VARS2 | ENSP00000248933 | ENSP00000441000 | seizure related 6 homolog (mouse)-like | valyl-tRNA synthetase 2, mitochondrial | 0.478 |