VPREB3 protein (Homo sapiens) - STRING network view

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VPREB3

pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells (123 aa)

Predicted Functional Partners:

IGLL1

0.760

VPREB1

0.618

QSOX1

0.576

BANK1

0.457

CXCL17

0.418

INHBE

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BANK1	VPREB3	ENSP00000320509	ENSP00000248948	B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.457
CXCL17	VPREB3	ENSP00000472467	ENSP00000248948	chemokine (C-X-C motif) ligand 17; Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.418
IGLL1	VPREB1	ENSP00000329312	ENSP00000385361	immunoglobulin lambda-like polypeptide 1; Critical for B-cell development	pre-B lymphocyte 1; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation	0.985
IGLL1	VPREB3	ENSP00000329312	ENSP00000248948	immunoglobulin lambda-like polypeptide 1; Critical for B-cell development	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.760
INHBE	VPREB3	ENSP00000266646	ENSP00000248948	inhibin, beta E; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.407
QSOX1	VPREB3	ENSP00000356574	ENSP00000248948	quiescin Q6 sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.576
VPREB1	IGLL1	ENSP00000385361	ENSP00000329312	pre-B lymphocyte 1; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation	immunoglobulin lambda-like polypeptide 1; Critical for B-cell development	0.985
VPREB1	VPREB3	ENSP00000385361	ENSP00000248948	pre-B lymphocyte 1; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	0.618
VPREB3	BANK1	ENSP00000248948	ENSP00000320509	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2	0.457
VPREB3	CXCL17	ENSP00000248948	ENSP00000472467	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	chemokine (C-X-C motif) ligand 17; Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections	0.418
VPREB3	IGLL1	ENSP00000248948	ENSP00000329312	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	immunoglobulin lambda-like polypeptide 1; Critical for B-cell development	0.760
VPREB3	INHBE	ENSP00000248948	ENSP00000266646	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	inhibin, beta E; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins	0.407
VPREB3	QSOX1	ENSP00000248948	ENSP00000356574	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	quiescin Q6 sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation	0.576
VPREB3	VPREB1	ENSP00000248948	ENSP00000385361	pre-B lymphocyte 3; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells	pre-B lymphocyte 1; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation	0.618

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