| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APPL1 | RFPL3 | ENSP00000288266 | ENSP00000249007 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction | ret finger protein-like 3 | 0.489 |
| FGF13 | NARS | ENSP00000359635 | ENSP00000256854 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | asparaginyl-tRNA synthetase | 0.511 |
| FGF13 | PAX6 | ENSP00000359635 | ENSP00000368401 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.609 |
| FGF13 | RFPL3 | ENSP00000359635 | ENSP00000249007 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | ret finger protein-like 3 | 0.416 |
| FGF13 | RFPL3-AS1 | ENSP00000359635 | ENSP00000383093 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | RFPL3 antisense RNA 1 | 0.439 |
| NARS | FGF13 | ENSP00000256854 | ENSP00000359635 | asparaginyl-tRNA synthetase | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | 0.511 |
| NARS | RFPL3 | ENSP00000256854 | ENSP00000249007 | asparaginyl-tRNA synthetase | ret finger protein-like 3 | 0.794 |
| NARS | RFPL3-AS1 | ENSP00000256854 | ENSP00000383093 | asparaginyl-tRNA synthetase | RFPL3 antisense RNA 1 | 0.811 |
| PAX6 | FGF13 | ENSP00000368401 | ENSP00000359635 | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | 0.609 |
| PAX6 | RFPL3 | ENSP00000368401 | ENSP00000249007 | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | ret finger protein-like 3 | 0.654 |
| RFPL3-AS1 | FGF13 | ENSP00000383093 | ENSP00000359635 | RFPL3 antisense RNA 1 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | 0.439 |
| RFPL3-AS1 | NARS | ENSP00000383093 | ENSP00000256854 | RFPL3 antisense RNA 1 | asparaginyl-tRNA synthetase | 0.811 |
| RFPL3-AS1 | RFPL3 | ENSP00000383093 | ENSP00000249007 | RFPL3 antisense RNA 1 | ret finger protein-like 3 | 0.871 |
| RFPL3 | APPL1 | ENSP00000249007 | ENSP00000288266 | ret finger protein-like 3 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction | 0.489 |
| RFPL3 | FGF13 | ENSP00000249007 | ENSP00000359635 | ret finger protein-like 3 | fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus | 0.416 |
| RFPL3 | NARS | ENSP00000249007 | ENSP00000256854 | ret finger protein-like 3 | asparaginyl-tRNA synthetase | 0.794 |
| RFPL3 | PAX6 | ENSP00000249007 | ENSP00000368401 | ret finger protein-like 3 | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.654 |
| RFPL3 | RFPL3-AS1 | ENSP00000249007 | ENSP00000383093 | ret finger protein-like 3 | RFPL3 antisense RNA 1 | 0.871 |
| RFPL3 | SSRP1 | ENSP00000249007 | ENSP00000278412 | ret finger protein-like 3 | structure specific recognition protein 1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the ree [...] | 0.405 |
| RFPL3 | SUPT16H | ENSP00000249007 | ENSP00000216297 | ret finger protein-like 3 | suppressor of Ty 16 homolog (S. cerevisiae); Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the [...] | 0.400 |
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