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ADH5 ADH5 ADH1B ADH1B CYP26C1 CYP26C1 DHRS3 DHRS3 CYP26A1 CYP26A1 ALDH1A2 ALDH1A2 RDH10 RDH10 ADH1A ADH1A CYP26B1 CYP26B1 ADH7 ADH7 ADH4 ADH4
"ALDH1A2" - aldehyde dehydrogenase 1 family, member A2 in Homo sapiens
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Predicted Interactions
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ALDH1A2aldehyde dehydrogenase 1 family, member A2; Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity) (518 aa)    
Predicted Functional Partners:
CYP26C1
cytochrome P450, family 26, subfamily C, polypeptide 1; Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate) (522 aa)
        score_image score_image score_image   0.992
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1; Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA (497 aa)
        score_image score_image score_image   0.982
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1 (512 aa)
        score_image score_image score_image   0.971
RDH10
retinol dehydrogenase 10 (all-trans); Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (341 aa)
      score_image score_image score_image score_image   0.963
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide; Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (374 aa)
          score_image score_image   0.946
DHRS3
dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH (302 aa)
      score_image score_image score_image score_image   0.944
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide (380 aa)
          score_image score_image   0.944
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide; Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism (394 aa)
          score_image score_image   0.943
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide (375 aa)
          score_image score_image   0.941
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide (375 aa)
          score_image score_image   0.939
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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