Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | RPS4Y1 | ribosomal protein S4, Y-linked 1 (263 aa) | ||||||||||||
Predicted Functional Partners:
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 | FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (133 aa) |
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0.999 | |||||||
 | RPS3A | ribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa) |
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0.999 | ||||||
 | RPS3 | ribosomal protein S3 (243 aa) |
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0.999 | ||||||
 | RPS8 | ribosomal protein S8 (208 aa) |
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0.999 | |||||||
 | RPS15 | ribosomal protein S15 (145 aa) |
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0.999 | ||||||
 | RPS6 | ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (249 aa) |
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0.999 | |||||||
 | RPS2 | ribosomal protein S2 (293 aa) |
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0.999 | ||||||
 | RPS7 | ribosomal protein S7; Required for rRNA maturation (194 aa) |
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0.999 | |||||||
 | RPS5 | ribosomal protein S5 (204 aa) |
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0.999 | |||||||
 | RPS16 | ribosomal protein S16 (146 aa) |
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0.999 | |||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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