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FBLN5 FBLN5 ATP6V0A2 ATP6V0A2 EFEMP2 EFEMP2 COL1A2 COL1A2 GORAB GORAB ADAMTS2 ADAMTS2 PCOLCE PCOLCE BMP1 BMP1 ABI3 ABI3 PCOLCE2 PCOLCE2 TLL1 TLL1
"ADAMTS2" - ADAM metallopeptidase with thrombospondin type 1 motif, 2 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 2; Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis (1211 aa)    
Predicted Functional Partners:
BMP1
bone morphogenetic protein 1 (986 aa)
      score_image   score_image score_image   0.941
TLL1
tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis (1013 aa)
          score_image score_image   0.921
PCOLCE
procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity (449 aa)
      score_image   score_image score_image   0.919
PCOLCE2
procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (415 aa)
      score_image   score_image score_image   0.910
ABI3
ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility (366 aa)
            score_image   0.812
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2 (443 aa)
      score_image     score_image   0.751
GORAB
golgin, RAB6-interacting (394 aa)
            score_image   0.730
FBLN5
fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling (448 aa)
            score_image   0.656
ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH (856 aa)
            score_image   0.653
COL1A2
collagen, type I, alpha 2 (1366 aa)
      score_image     score_image   0.632
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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