KIAA1244 protein (Homo sapiens) - STRING network view

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Score

KIAA1244

KIAA1244 (2177 aa)

Predicted Functional Partners:

PHB2

0.824

PTH

0.576

CHD8

0.564

FAM5C

0.501

PERP

0.478

PPP1R35

0.416

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD8	KIAA1244	ENSP00000382863	ENSP00000251691	chromodomain helicase DNA binding protein 8	KIAA1244	0.564
FAM5C	KIAA1244	ENSP00000356432	ENSP00000251691	family with sequence similarity 5, member C	KIAA1244	0.501
KIAA1244	CHD8	ENSP00000251691	ENSP00000382863	KIAA1244	chromodomain helicase DNA binding protein 8	0.564
KIAA1244	FAM5C	ENSP00000251691	ENSP00000356432	KIAA1244	family with sequence similarity 5, member C	0.501
KIAA1244	PERP	ENSP00000251691	ENSP00000397157	KIAA1244	PERP, TP53 apoptosis effector; Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity)	0.478
KIAA1244	PHB2	ENSP00000251691	ENSP00000441875	KIAA1244	prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging	0.824
KIAA1244	PPP1R35	ENSP00000251691	ENSP00000292330	KIAA1244	protein phosphatase 1, regulatory subunit 35; Inhibits PPP1CA phosphatase activity	0.416
KIAA1244	PTH	ENSP00000251691	ENSP00000282091	KIAA1244	parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells	0.576
PERP	KIAA1244	ENSP00000397157	ENSP00000251691	PERP, TP53 apoptosis effector; Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity)	KIAA1244	0.478
PHB2	KIAA1244	ENSP00000441875	ENSP00000251691	prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging	KIAA1244	0.824
PPP1R35	KIAA1244	ENSP00000292330	ENSP00000251691	protein phosphatase 1, regulatory subunit 35; Inhibits PPP1CA phosphatase activity	KIAA1244	0.416
PTH	KIAA1244	ENSP00000282091	ENSP00000251691	parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells	KIAA1244	0.576

Experiments

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