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STRINGSTRING
EFEMP1 EFEMP1 RUNDC3B RUNDC3B PCDHGA12 PCDHGA12 DDX51 DDX51 CACNA1G CACNA1G
"PCDHGA12" - protocadherin gamma subfamily A, 12 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
PCDHGA12protocadherin gamma subfamily A, 12; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (932 aa)    
Predicted Functional Partners:
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit (2377 aa)
            score_image   0.495
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits (By similarity) (666 aa)
            score_image   0.450
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1; Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (493 aa)
            score_image   0.420
RUNDC3B
RUN domain containing 3B (473 aa)
            score_image   0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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