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SDHD SDHD SDHC SDHC GLS2 GLS2 SDHB SDHB PGLS PGLS H6PD H6PD G6PD G6PD TKT TKT PGD PGD TALDO1 TALDO1 GNPDA1 GNPDA1
"PGLS" - 6-phosphogluconolactonase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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Predicted Interactions
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PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate (258 aa)    
Predicted Functional Partners:
G6PD
glucose-6-phosphate dehydrogenase; Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power (545 aa)
score_image   score_image     score_image score_image   0.992
PGD
phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) (483 aa)
score_image     score_image   score_image score_image   0.988
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates (791 aa)
score_image   score_image     score_image score_image score_image 0.960
GNPDA1
glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) (289 aa)
            score_image   0.860
TKT
transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (623 aa)
score_image     score_image     score_image   0.836
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity) (159 aa)
            score_image   0.810
SDHC
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (169 aa)
            score_image   0.771
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip); Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (280 aa)
            score_image   0.741
GLS2
glutaminase 2 (liver, mitochondrial); Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation (602 aa)
            score_image   0.732
TALDO1
transaldolase 1; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) (337 aa)
score_image     score_image     score_image   0.725
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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