TUBGCP2 protein (Homo sapiens) - STRING network view

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TUBGCP2

tubulin, gamma complex associated protein 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (902 aa)

Predicted Functional Partners:

TUBGCP3

0.999

TUBGCP6

0.999

TUBGCP4

0.999

TUBG1

0.995

TUBG2

0.993

MZT2B

0.990

MZT1

0.988

NEDD1

0.983

CKAP5

0.982

PCNT

0.973

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKAP5	NEDD1	ENSP00000432768	ENSP00000451211	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	neural precursor cell expressed, developmentally down-regulated 1; Required for mitosis progression. Promotes the nucleation of microtubules from the spindle	0.928
CKAP5	PCNT	ENSP00000432768	ENSP00000352572	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	pericentrin; Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome	0.929
CKAP5	TUBG1	ENSP00000432768	ENSP00000251413	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma 1; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation	0.963
CKAP5	TUBG2	ENSP00000432768	ENSP00000251412	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma 2; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity)	0.963
CKAP5	TUBGCP2	ENSP00000432768	ENSP00000252936	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma complex associated protein 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.982
CKAP5	TUBGCP3	ENSP00000432768	ENSP00000261965	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma complex associated protein 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.963
CKAP5	TUBGCP4	ENSP00000432768	ENSP00000456648	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma complex associated protein 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.909
CKAP5	TUBGCP6	ENSP00000432768	ENSP00000248846	cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles	tubulin, gamma complex associated protein 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.953
MZT1	MZT2B	ENSP00000367049	ENSP00000281871	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	mitotic spindle organizing protein 2B	0.988
MZT1	TUBG1	ENSP00000367049	ENSP00000251413	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma 1; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation	0.999
MZT1	TUBG2	ENSP00000367049	ENSP00000251412	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma 2; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity)	0.450
MZT1	TUBGCP2	ENSP00000367049	ENSP00000252936	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma complex associated protein 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.988
MZT1	TUBGCP3	ENSP00000367049	ENSP00000261965	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma complex associated protein 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.995
MZT1	TUBGCP4	ENSP00000367049	ENSP00000456648	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma complex associated protein 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.998
MZT1	TUBGCP6	ENSP00000367049	ENSP00000248846	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	tubulin, gamma complex associated protein 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.999
MZT2B	MZT1	ENSP00000281871	ENSP00000367049	mitotic spindle organizing protein 2B	mitotic spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome	0.988
MZT2B	TUBG1	ENSP00000281871	ENSP00000251413	mitotic spindle organizing protein 2B	tubulin, gamma 1; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation	0.999
MZT2B	TUBGCP2	ENSP00000281871	ENSP00000252936	mitotic spindle organizing protein 2B	tubulin, gamma complex associated protein 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.990
MZT2B	TUBGCP3	ENSP00000281871	ENSP00000261965	mitotic spindle organizing protein 2B	tubulin, gamma complex associated protein 3; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.990
MZT2B	TUBGCP4	ENSP00000281871	ENSP00000456648	mitotic spindle organizing protein 2B	tubulin, gamma complex associated protein 4; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome	0.998

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