CEP85 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CEP85

centrosomal protein 85kDa (762 aa)

Predicted Functional Partners:

RBM34

0.673

DNAJC16

0.670

WRAP73

0.620

LRRC47

0.597

LUZP1

0.570

CEP192

0.570

SLC25A33

0.539

EMC1

0.537

UBE2J2

0.532

UBC

0.483

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEP192	CEP85	ENSP00000427550	ENSP00000252992	centrosomal protein 192kDa; Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication	centrosomal protein 85kDa	0.570
CEP192	UBC	ENSP00000427550	ENSP00000344818	centrosomal protein 192kDa; Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication	ubiquitin C	0.834
CEP85	CEP192	ENSP00000252992	ENSP00000427550	centrosomal protein 85kDa	centrosomal protein 192kDa; Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication	0.570
CEP85	DNAJC16	ENSP00000252992	ENSP00000365007	centrosomal protein 85kDa	DnaJ (Hsp40) homolog, subfamily C, member 16	0.670
CEP85	EMC1	ENSP00000252992	ENSP00000420608	centrosomal protein 85kDa	ER membrane protein complex subunit 1	0.537
CEP85	LRRC47	ENSP00000252992	ENSP00000367498	centrosomal protein 85kDa	leucine rich repeat containing 47	0.597
CEP85	LUZP1	ENSP00000252992	ENSP00000303758	centrosomal protein 85kDa	leucine zipper protein 1	0.570
CEP85	RBM34	ENSP00000252992	ENSP00000386226	centrosomal protein 85kDa	RNA binding motif protein 34	0.673
CEP85	SLC25A33	ENSP00000252992	ENSP00000306328	centrosomal protein 85kDa	solute carrier family 25 (pyrimidine nucleotide carrier), member 33; Probable mitochondrial transporter which participates in dendritic cell endocytosis. May associate with mitochondrial oxidative phosphorylation	0.539
CEP85	UBC	ENSP00000252992	ENSP00000344818	centrosomal protein 85kDa	ubiquitin C	0.483
CEP85	UBE2J2	ENSP00000252992	ENSP00000383719	centrosomal protein 85kDa	ubiquitin-conjugating enzyme E2, J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity)	0.532
CEP85	WRAP73	ENSP00000252992	ENSP00000270708	centrosomal protein 85kDa	WD repeat containing, antisense to TP73	0.620
DNAJC16	CEP85	ENSP00000365007	ENSP00000252992	DnaJ (Hsp40) homolog, subfamily C, member 16	centrosomal protein 85kDa	0.670
DNAJC16	EMC1	ENSP00000365007	ENSP00000420608	DnaJ (Hsp40) homolog, subfamily C, member 16	ER membrane protein complex subunit 1	0.673
DNAJC16	LRRC47	ENSP00000365007	ENSP00000367498	DnaJ (Hsp40) homolog, subfamily C, member 16	leucine rich repeat containing 47	0.652
DNAJC16	LUZP1	ENSP00000365007	ENSP00000303758	DnaJ (Hsp40) homolog, subfamily C, member 16	leucine zipper protein 1	0.642
DNAJC16	SLC25A33	ENSP00000365007	ENSP00000306328	DnaJ (Hsp40) homolog, subfamily C, member 16	solute carrier family 25 (pyrimidine nucleotide carrier), member 33; Probable mitochondrial transporter which participates in dendritic cell endocytosis. May associate with mitochondrial oxidative phosphorylation	0.591
DNAJC16	UBC	ENSP00000365007	ENSP00000344818	DnaJ (Hsp40) homolog, subfamily C, member 16	ubiquitin C	0.541
DNAJC16	UBE2J2	ENSP00000365007	ENSP00000383719	DnaJ (Hsp40) homolog, subfamily C, member 16	ubiquitin-conjugating enzyme E2, J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity)	0.638
DNAJC16	WRAP73	ENSP00000365007	ENSP00000270708	DnaJ (Hsp40) homolog, subfamily C, member 16	WD repeat containing, antisense to TP73	0.705

page 1 of 4

Experiments

Cooccurrence

Textmining

Neighborhood

Coexpression

Fusion

Databases

© STRING Consortium 2017

Credits

Access

Info

About