node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIRH1A | HEATR1 | ENSP00000327179 | ENSP00000355541 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.988 |
CIRH1A | NOL11 | ENSP00000327179 | ENSP00000253247 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | nucleolar protein 11 | 0.978 |
CIRH1A | NOP14 | ENSP00000327179 | ENSP00000315674 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) | 0.991 |
CIRH1A | UTP15 | ENSP00000327179 | ENSP00000296792 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) | 0.993 |
CIRH1A | WDR12 | ENSP00000327179 | ENSP00000261015 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.891 |
CIRH1A | WDR36 | ENSP00000327179 | ENSP00000423067 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 | 0.994 |
CIRH1A | WDR43 | ENSP00000327179 | ENSP00000384302 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | WD repeat domain 43 | 0.999 |
CIRH1A | WDR75 | ENSP00000327179 | ENSP00000314193 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | WD repeat domain 75 | 0.992 |
HEATR1 | CIRH1A | ENSP00000355541 | ENSP00000327179 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | 0.988 |
HEATR1 | NOL11 | ENSP00000355541 | ENSP00000253247 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | nucleolar protein 11 | 0.553 |
HEATR1 | NOP14 | ENSP00000355541 | ENSP00000315674 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) | 0.994 |
HEATR1 | UTP15 | ENSP00000355541 | ENSP00000296792 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) | 0.997 |
HEATR1 | WDR12 | ENSP00000355541 | ENSP00000261015 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.879 |
HEATR1 | WDR36 | ENSP00000355541 | ENSP00000423067 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 | 0.999 |
HEATR1 | WDR43 | ENSP00000355541 | ENSP00000384302 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 43 | 0.997 |
HEATR1 | WDR75 | ENSP00000355541 | ENSP00000314193 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | WD repeat domain 75 | 0.998 |
LRRC37A3 | NOL11 | ENSP00000325713 | ENSP00000253247 | leucine rich repeat containing 37, member A3 | nucleolar protein 11 | 0.658 |
NOL11 | CIRH1A | ENSP00000253247 | ENSP00000327179 | nucleolar protein 11 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | 0.978 |
NOL11 | HEATR1 | ENSP00000253247 | ENSP00000355541 | nucleolar protein 11 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.553 |
NOL11 | LRRC37A3 | ENSP00000253247 | ENSP00000325713 | nucleolar protein 11 | leucine rich repeat containing 37, member A3 | 0.658 |