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STRINGSTRING
EPPIN EPPIN SPAG11B SPAG11B DEFB126 DEFB126 DEFB124 DEFB124 DEFB118 DEFB118 DEFB1 DEFB1 CAMP CAMP DEFB121 DEFB121 DEFB135 DEFB135 DEFB123 DEFB123 DEFB119 DEFB119
"DEFB118" - defensin, beta 118 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB118defensin, beta 118; Has antibacterial activity (Potential) (123 aa)    
Predicted Functional Partners:
DEFB121
defensin, beta 121; Has antibacterial activity (Potential) (76 aa)
             score_image   0.703
DEFB123
defensin, beta 123; Has antibacterial activity (Potential) (67 aa)
             score_image   0.645
DEFB135
defensin, beta 135; Has antibacterial activity (Potential) (77 aa)
             score_image   0.597
DEFB124
defensin, beta 124; Has antibacterial activity (Potential) (71 aa)
             score_image   0.553
DEFB1
defensin, beta 1; Has bactericidal activity (By similarity) (68 aa)
             score_image   0.538
CAMP
cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity (170 aa)
             score_image   0.505
DEFB119
defensin, beta 119; Has antibacterial activity (Potential) (88 aa)
             score_image   0.499
SPAG11B
sperm associated antigen 11B (133 aa)
             score_image   0.483
EPPIN
epididymal peptidase inhibitor; Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility (179 aa)
             score_image   0.472
DEFB126
defensin, beta 126; Has antibacterial activity (Potential) (111 aa)
             score_image   0.453
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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