Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMOTL2 | KRT15 | ENSP00000249883 | ENSP00000254043 | angiomotin like 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC | keratin 15 | 0.657 |
AMOTL2 | UBC | ENSP00000249883 | ENSP00000344818 | angiomotin like 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC | ubiquitin C | 0.911 |
ARC | KRT15 | ENSP00000349022 | ENSP00000254043 | activity-regulated cytoskeleton-associated protein; Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration | keratin 15 | 0.633 |
ARC | UBC | ENSP00000349022 | ENSP00000344818 | activity-regulated cytoskeleton-associated protein; Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration | ubiquitin C | 0.681 |
C1orf216 | KRT15 | ENSP00000425166 | ENSP00000254043 | chromosome 1 open reading frame 216 | keratin 15 | 0.595 |
CCDC120 | KRT15 | ENSP00000416445 | ENSP00000254043 | coiled-coil domain containing 120 | keratin 15 | 0.669 |
HR | KRT15 | ENSP00000370826 | ENSP00000254043 | hairless homolog (mouse); May act as a transcription factor that could act on to regulate one of the phases of hair growth | keratin 15 | 0.681 |
KRT15 | AMOTL2 | ENSP00000254043 | ENSP00000249883 | keratin 15 | angiomotin like 2; Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC | 0.657 |
KRT15 | ARC | ENSP00000254043 | ENSP00000349022 | keratin 15 | activity-regulated cytoskeleton-associated protein; Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration | 0.633 |
KRT15 | C1orf216 | ENSP00000254043 | ENSP00000425166 | keratin 15 | chromosome 1 open reading frame 216 | 0.595 |
KRT15 | CCDC120 | ENSP00000254043 | ENSP00000416445 | keratin 15 | coiled-coil domain containing 120 | 0.669 |
KRT15 | HR | ENSP00000254043 | ENSP00000370826 | keratin 15 | hairless homolog (mouse); May act as a transcription factor that could act on to regulate one of the phases of hair growth | 0.681 |
KRT15 | KRT6A | ENSP00000254043 | ENSP00000369317 | keratin 15 | keratin 6A | 0.646 |
KRT15 | LDOC1 | ENSP00000254043 | ENSP00000359557 | keratin 15 | leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers | 0.590 |
KRT15 | PRL | ENSP00000254043 | ENSP00000302150 | keratin 15 | prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | 0.800 |
KRT15 | TELO2 | ENSP00000254043 | ENSP00000262319 | keratin 15 | TEL2, telomere maintenance 2, homolog (S. cerevisiae); Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complex [...] | 0.688 |
KRT15 | UBC | ENSP00000254043 | ENSP00000344818 | keratin 15 | ubiquitin C | 0.806 |
KRT6A | KRT15 | ENSP00000369317 | ENSP00000254043 | keratin 6A | keratin 15 | 0.646 |
KRT6A | UBC | ENSP00000369317 | ENSP00000344818 | keratin 6A | ubiquitin C | 0.867 |
LDOC1 | KRT15 | ENSP00000359557 | ENSP00000254043 | leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers | keratin 15 | 0.590 |
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