node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGA | FSHB | ENSP00000358595 | ENSP00000254122 | glycoprotein hormones, alpha polypeptide | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | 0.999 |
CGA | FSHR | ENSP00000358595 | ENSP00000384708 | glycoprotein hormones, alpha polypeptide | follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase | 0.994 |
CGA | INHA | ENSP00000358595 | ENSP00000243786 | glycoprotein hormones, alpha polypeptide | inhibin, alpha; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.906 |
CGA | INHBA | ENSP00000358595 | ENSP00000242208 | glycoprotein hormones, alpha polypeptide | inhibin, beta A; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.908 |
CGA | INHBB | ENSP00000358595 | ENSP00000295228 | glycoprotein hormones, alpha polypeptide | inhibin, beta B; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.903 |
CGA | INHBC | ENSP00000358595 | ENSP00000308716 | glycoprotein hormones, alpha polypeptide | inhibin, beta C; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.900 |
CGA | INHBE | ENSP00000358595 | ENSP00000266646 | glycoprotein hormones, alpha polypeptide | inhibin, beta E; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.900 |
FSHB | CGA | ENSP00000254122 | ENSP00000358595 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | glycoprotein hormones, alpha polypeptide | 0.999 |
FSHB | FSHR | ENSP00000254122 | ENSP00000384708 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase | 0.999 |
FSHB | GNAS | ENSP00000254122 | ENSP00000360141 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity) | 0.900 |
FSHB | GNB1 | ENSP00000254122 | ENSP00000367869 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.900 |
FSHB | GNGT1 | ENSP00000254122 | ENSP00000248572 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) | 0.900 |
FSHB | INHA | ENSP00000254122 | ENSP00000243786 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | inhibin, alpha; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.920 |
FSHB | INHBA | ENSP00000254122 | ENSP00000242208 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | inhibin, beta A; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.929 |
FSHB | INHBB | ENSP00000254122 | ENSP00000295228 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | inhibin, beta B; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.930 |
FSHB | INHBC | ENSP00000254122 | ENSP00000308716 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | inhibin, beta C; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.901 |
FSHB | INHBE | ENSP00000254122 | ENSP00000266646 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | inhibin, beta E; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins | 0.900 |
FSHR | CGA | ENSP00000384708 | ENSP00000358595 | follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase | glycoprotein hormones, alpha polypeptide | 0.994 |
FSHR | FSHB | ENSP00000384708 | ENSP00000254122 | follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | 0.999 |
FSHR | GNAS | ENSP00000384708 | ENSP00000360141 | follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase | GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity) | 0.922 |