node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP2B2 | OC90 | ENSP00000324172 | ENSP00000254627 | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | 0.747 |
ATP2B2 | OTOP1 | ENSP00000324172 | ENSP00000296358 | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 1; Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity) | 0.777 |
ATP2B2 | OTOP2 | ENSP00000324172 | ENSP00000332528 | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 2 | 0.476 |
ATP2B2 | OTOP3 | ENSP00000324172 | ENSP00000328090 | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 3 | 0.476 |
ATP2B2 | SLC26A4 | ENSP00000324172 | ENSP00000265715 | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.510 |
ATP2B4 | OC90 | ENSP00000350310 | ENSP00000254627 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | 0.680 |
ATP2B4 | OTOP1 | ENSP00000350310 | ENSP00000296358 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 1; Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity) | 0.706 |
ATP2B4 | OTOP2 | ENSP00000350310 | ENSP00000332528 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 2 | 0.418 |
ATP2B4 | OTOP3 | ENSP00000350310 | ENSP00000328090 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | otopetrin 3 | 0.418 |
ATP2B4 | SLC26A4 | ENSP00000350310 | ENSP00000265715 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.439 |
HHLA1 | OC90 | ENSP00000407107 | ENSP00000254627 | HERV-H LTR-associating 1 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | 0.868 |
NOX3 | OC90 | ENSP00000159060 | ENSP00000254627 | NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | 0.644 |
NOX3 | OTOP1 | ENSP00000159060 | ENSP00000296358 | NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity | otopetrin 1; Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity) | 0.584 |
OC90 | ATP2B2 | ENSP00000254627 | ENSP00000324172 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.747 |
OC90 | ATP2B4 | ENSP00000254627 | ENSP00000350310 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.680 |
OC90 | HHLA1 | ENSP00000254627 | ENSP00000407107 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | HERV-H LTR-associating 1 | 0.868 |
OC90 | NOX3 | ENSP00000254627 | ENSP00000159060 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity | 0.644 |
OC90 | OTOG | ENSP00000254627 | ENSP00000382323 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | 0.569 |
OC90 | OTOL1 | ENSP00000254627 | ENSP00000330808 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | otolin 1 | 0.729 |
OC90 | OTOP1 | ENSP00000254627 | ENSP00000296358 | otoconin 90; It is unlikely that this protein has phospholipase A2 activity | otopetrin 1; Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity) | 0.798 |