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CHDH CHDH MBOAT1 MBOAT1 EPT1 EPT1 PTDSS2 PTDSS2 PISD PISD MBOAT2 MBOAT2 CEPT1 CEPT1 PEMT PEMT CHPT1 CHPT1 PTDSS1 PTDSS1 LCAT LCAT
"PEMT" - phosphatidylethanolamine N-methyltransferase in Homo sapiens
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protein of unknown 3D structure
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Score
PEMTphosphatidylethanolamine N-methyltransferase (236 aa)    
Predicted Functional Partners:
LCAT
lecithin-cholesterol acyltransferase; Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16-0-18-2 or 18-O-18-2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-contain [...] (440 aa)
      score_image score_image score_image score_image   0.977
CEPT1
choline/ethanolamine phosphotransferase 1; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (416 aa)
        score_image score_image score_image   0.974
PISD
phosphatidylserine decarboxylase (375 aa)
      score_image score_image score_image score_image   0.970
PTDSS2
phosphatidylserine synthase 2; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine (487 aa)
          score_image score_image   0.968
CHPT1
choline phosphotransferase 1 (406 aa)
        score_image score_image score_image   0.964
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific); Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via ’Kennedy’ pathway (397 aa)
        score_image score_image score_image   0.958
PTDSS1
phosphatidylserine synthase 1; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (473 aa)
          score_image score_image   0.953
MBOAT1
membrane bound O-acyltransferase domain containing 1; Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L- serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3- phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (495 aa)
        score_image score_image score_image   0.941
MBOAT2
membrane bound O-acyltransferase domain containing 2; Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2- diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phosph [...] (520 aa)
        score_image score_image score_image   0.935
CHDH
choline dehydrogenase (594 aa)
          score_image score_image   0.928
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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