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STRINGSTRING
FAM3C FAM3C HELT HELT SELV SELV MEST MEST GPR83 GPR83 YIPF7 YIPF7 IER3IP1 IER3IP1 AVEN AVEN CYSTM1 CYSTM1 YIPF5 YIPF5 UBC UBC
"IER3IP1" - immediate early response 3 interacting protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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[Homology]
Score
IER3IP1immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) (82 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.899
YIPF5
Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi (257 aa)
      score_image score_image   score_image   0.877
YIPF7
Yip1 domain family, member 7 (280 aa)
        score_image   score_image   0.747
SELV
selenoprotein V ; May be involved in a redox-related process (Potential) (346 aa)
            score_image   0.720
GPR83
G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor (423 aa)
            score_image   0.720
MEST
mesoderm specific transcript homolog (mouse) (335 aa)
            score_image   0.704
FAM3C
family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition (227 aa)
        score_image       0.644
CYSTM1
cysteine-rich transmembrane module containing 1 (97 aa)
        score_image       0.644
HELT
helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity) (327 aa)
            score_image   0.636
AVEN
apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1 (362 aa)
            score_image   0.634
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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