CFHR5 protein (Homo sapiens) - STRING network view

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CFHR5

complement factor H-related 5; Involved in complement regulation (569 aa)

Predicted Functional Partners:

C3

0.966

MUC5B

0.576

CNDP2

0.516

CD46

0.505

COL4A3

0.503

RRM2B

0.489

ARMS2

0.472

COL4A4

0.459

RBMS2

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMS2	C3	ENSP00000436682	ENSP00000245907	age-related maculopathy susceptibility 2	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	0.468
ARMS2	CFHR5	ENSP00000436682	ENSP00000256785	age-related maculopathy susceptibility 2	complement factor H-related 5; Involved in complement regulation	0.472
C3	ARMS2	ENSP00000245907	ENSP00000436682	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	age-related maculopathy susceptibility 2	0.468
C3	CD46	ENSP00000245907	ENSP00000313875	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	CD46 molecule, complement regulatory protein	0.998
C3	CFHR5	ENSP00000245907	ENSP00000256785	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	complement factor H-related 5; Involved in complement regulation	0.966
C3	RBMS2	ENSP00000245907	ENSP00000262031	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	RNA binding motif, single stranded interacting protein 2	0.639
CD46	C3	ENSP00000313875	ENSP00000245907	CD46 molecule, complement regulatory protein	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	0.998
CD46	CFHR5	ENSP00000313875	ENSP00000256785	CD46 molecule, complement regulatory protein	complement factor H-related 5; Involved in complement regulation	0.505
CFHR5	ARMS2	ENSP00000256785	ENSP00000436682	complement factor H-related 5; Involved in complement regulation	age-related maculopathy susceptibility 2	0.472
CFHR5	C3	ENSP00000256785	ENSP00000245907	complement factor H-related 5; Involved in complement regulation	complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates	0.966
CFHR5	CD46	ENSP00000256785	ENSP00000313875	complement factor H-related 5; Involved in complement regulation	CD46 molecule, complement regulatory protein	0.505
CFHR5	CNDP2	ENSP00000256785	ENSP00000325548	complement factor H-related 5; Involved in complement regulation	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	0.516
CFHR5	COL4A3	ENSP00000256785	ENSP00000379823	complement factor H-related 5; Involved in complement regulation	collagen, type IV, alpha 3 (Goodpasture antigen)	0.503
CFHR5	COL4A4	ENSP00000256785	ENSP00000379866	complement factor H-related 5; Involved in complement regulation	collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.459
CFHR5	MUC5B	ENSP00000256785	ENSP00000436812	complement factor H-related 5; Involved in complement regulation	mucin 5B, oligomeric mucus/gel-forming	0.576
CFHR5	RBMS2	ENSP00000256785	ENSP00000262031	complement factor H-related 5; Involved in complement regulation	RNA binding motif, single stranded interacting protein 2	0.400
CFHR5	RRM2B	ENSP00000256785	ENSP00000251810	complement factor H-related 5; Involved in complement regulation	ribonucleotide reductase M2 B (TP53 inducible)	0.489
CNDP2	CFHR5	ENSP00000325548	ENSP00000256785	CNDP dipeptidase 2 (metallopeptidase M20 family); Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells	complement factor H-related 5; Involved in complement regulation	0.516
COL4A3	CFHR5	ENSP00000379823	ENSP00000256785	collagen, type IV, alpha 3 (Goodpasture antigen)	complement factor H-related 5; Involved in complement regulation	0.503
COL4A3	COL4A4	ENSP00000379823	ENSP00000379866	collagen, type IV, alpha 3 (Goodpasture antigen)	collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.929

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