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GATSL2 GATSL2 ABHD4 ABHD4 SELT SELT CNR1 CNR1 ABHD12 ABHD12 DAGLA DAGLA NAPEPLD NAPEPLD FAAH FAAH ARRDC3 ARRDC3 MGLL MGLL NAAA NAAA
"DAGLA" - diacylglycerol lipase, alpha in Homo sapiens
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Predicted Interactions
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DAGLAdiacylglycerol lipase, alpha; Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses (1042 aa)    
Predicted Functional Partners:
MGLL
monoglyceride lipase; Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (313 aa)
          score_image score_image   0.965
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D; Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity) (393 aa)
            score_image   0.882
ABHD4
abhydrolase domain containing 4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lys [...] (342 aa)
            score_image   0.622
ARRDC3
arrestin domain containing 3 (414 aa)
            score_image   0.611
FAAH
fatty acid amide hydrolase; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (579 aa)
            score_image   0.586
ABHD12
abhydrolase domain containing 12 (404 aa)
            score_image   0.563
CNR1
cannabinoid receptor 1 (brain) (472 aa)
            score_image   0.533
NAAA
N-acylethanolamine acid amidase; Degrades bioactive fatty acid amides to their corresponding acids, with the following preference- N- palmitoylethanolamine > N-myristoylethanolamine > N- lauroylethanolamine = N-stearoylethanolamine > N- arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine (359 aa)
            score_image   0.524
SELT
selenoprotein T precursor (195 aa)
            score_image   0.502
GATSL2
GATS protein-like 2 (329 aa)
            score_image   0.493
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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