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BMP2 BMP2 SMAD9 SMAD9 BMP4 BMP4 SMAD1 SMAD1 BMP6 BMP6 SMAD5 SMAD5 BMP7 BMP7 ACVR1 ACVR1 AMHR2 AMHR2 AMH AMH FKBP1A FKBP1A
"AMHR2" - anti-Mullerian hormone receptor, type II in Homo sapiens
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AMHR2anti-Mullerian hormone receptor, type II; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone (573 aa)    
Predicted Functional Partners:
AMH
anti-Mullerian hormone; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (560 aa)
        score_image score_image score_image   0.992
SMAD9
SMAD family member 9; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD) (467 aa)
      score_image   score_image score_image   0.957
SMAD5
SMAD family member 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD) (464 aa)
      score_image   score_image score_image   0.956
ACVR1
activin A receptor, type I; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity) (509 aa)
      score_image score_image score_image score_image score_image 0.946
SMAD1
SMAD family member 1; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (465 aa)
      score_image   score_image score_image   0.937
FKBP1A
FK506 binding protein 1A, 12kDa; Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (108 aa)
          score_image score_image   0.901
BMP7
bone morphogenetic protein 7; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (431 aa)
          score_image score_image   0.885
BMP4
bone morphogenetic protein 4; Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity) (408 aa)
          score_image score_image   0.883
BMP2
bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
          score_image score_image   0.883
BMP6
bone morphogenetic protein 6; Induces cartilage and bone formation (513 aa)
          score_image score_image   0.872
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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