| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CNNM2 | MAGT1 | ENSP00000358894 | ENSP00000354649 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | 0.750 |
| CNNM2 | MMGT1 | ENSP00000358894 | ENSP00000306220 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | 0.566 |
| CNNM2 | MRS2 | ENSP00000358894 | ENSP00000367637 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | 0.787 |
| CNNM2 | NIPA1 | ENSP00000358894 | ENSP00000337452 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.488 |
| CNNM2 | SLC41A2 | ENSP00000358894 | ENSP00000258538 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | solute carrier family 41, member 2; Acts as a plasma-membrane magnesium transporter | 0.695 |
| CNNM2 | TRPM6 | ENSP00000358894 | ENSP00000354006 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | transient receptor potential cation channel, subfamily M, member 6; Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region | 0.621 |
| CNNM2 | TRPM7 | ENSP00000358894 | ENSP00000320239 | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | transient receptor potential cation channel, subfamily M, member 7; Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1) | 0.588 |
| CNNM4 | MAGT1 | ENSP00000366275 | ENSP00000354649 | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | 0.403 |
| CNNM4 | MMGT1 | ENSP00000366275 | ENSP00000306220 | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | 0.418 |
| CNNM4 | MRS2 | ENSP00000366275 | ENSP00000367637 | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | 0.643 |
| CNNM4 | NIPA1 | ENSP00000366275 | ENSP00000337452 | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.484 |
| CNNM4 | SLC41A2 | ENSP00000366275 | ENSP00000258538 | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | solute carrier family 41, member 2; Acts as a plasma-membrane magnesium transporter | 0.519 |
| HOMEZ | SLC41A2 | ENSP00000350049 | ENSP00000258538 | homeobox and leucine zipper encoding; May function as a transcriptional regulator | solute carrier family 41, member 2; Acts as a plasma-membrane magnesium transporter | 0.569 |
| MAGT1 | CNNM2 | ENSP00000354649 | ENSP00000358894 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | cyclin M2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity) | 0.750 |
| MAGT1 | CNNM4 | ENSP00000354649 | ENSP00000366275 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | cyclin M4; Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | 0.403 |
| MAGT1 | MGAM | ENSP00000354649 | ENSP00000447378 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | maltase-glucoamylase (alpha-glucosidase); May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing | 0.722 |
| MAGT1 | MMGT1 | ENSP00000354649 | ENSP00000306220 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) | 0.716 |
| MAGT1 | MRS2 | ENSP00000354649 | ENSP00000367637 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix | 0.705 |
| MAGT1 | NIPA1 | ENSP00000354649 | ENSP00000337452 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) | 0.539 |
| MAGT1 | SLC41A2 | ENSP00000354649 | ENSP00000258538 | magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells | solute carrier family 41, member 2; Acts as a plasma-membrane magnesium transporter | 0.655 |
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