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STRINGSTRING
C15orf26 C15orf26 WDR52 WDR52 BTBD9 BTBD9 TMEM45B TMEM45B FAM108C1 FAM108C1 UBC UBC C1orf106 C1orf106 CC2D1A CC2D1A
"FAM108C1" - family with sequence similarity 108, member C1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM108C1family with sequence similarity 108, member C1 (329 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.731
CC2D1A
coiled-coil and C2 domain containing 1A; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasm [...] (951 aa)
            score_image   0.518
C1orf106
chromosome 1 open reading frame 106 (663 aa)
            score_image   0.502
C15orf26
chromosome 15 open reading frame 26 (301 aa)
            score_image   0.480
BTBD9
BTB (POZ) domain containing 9 (612 aa)
            score_image   0.473
TMEM45B
transmembrane protein 45B (275 aa)
            score_image   0.472
WDR52
WD repeat domain 52 (1854 aa)
            score_image   0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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