| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CIB2 | COPB2 | ENSP00000258930 | ENSP00000329419 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | coatomer protein complex, subunit beta 2 (beta prime); The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding [...] | 0.597 |
| CIB2 | CORO2B | ENSP00000258930 | ENSP00000454783 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | 0.825 |
| CIB2 | DONSON | ENSP00000258930 | ENSP00000307143 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | downstream neighbor of SON; Essential for DNA amplification in the ovary and required for cell proliferation during development (By similarity) | 0.581 |
| CIB2 | ITGA11 | ENSP00000258930 | ENSP00000327290 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | integrin, alpha 11; Integrin alpha-11/beta-1 is a receptor for collagen | 0.803 |
| CIB2 | KIF23 | ENSP00000258930 | ENSP00000260363 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | kinesin family member 23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro | 0.705 |
| CIB2 | MYOD1 | ENSP00000258930 | ENSP00000250003 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | 0.576 |
| CIB2 | PDZD7 | ENSP00000258930 | ENSP00000359234 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | PDZ domain containing 7 | 0.756 |
| CIB2 | POTEE | ENSP00000258930 | ENSP00000439189 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | POTE ankyrin domain family member E | 0.541 |
| CIB2 | PRKDC | ENSP00000258930 | ENSP00000313420 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | protein kinase, DNA-activated, catalytic polypeptide | 0.583 |
| CIB2 | TLE3 | ENSP00000258930 | ENSP00000452871 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) | 0.867 |
| COPB2 | CIB2 | ENSP00000329419 | ENSP00000258930 | coatomer protein complex, subunit beta 2 (beta prime); The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding [...] | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | 0.597 |
| COPB2 | DONSON | ENSP00000329419 | ENSP00000307143 | coatomer protein complex, subunit beta 2 (beta prime); The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding [...] | downstream neighbor of SON; Essential for DNA amplification in the ovary and required for cell proliferation during development (By similarity) | 0.563 |
| CORO2B | CIB2 | ENSP00000454783 | ENSP00000258930 | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | 0.825 |
| CORO2B | ITGA11 | ENSP00000454783 | ENSP00000327290 | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | integrin, alpha 11; Integrin alpha-11/beta-1 is a receptor for collagen | 0.759 |
| CORO2B | KIF23 | ENSP00000454783 | ENSP00000260363 | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | kinesin family member 23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro | 0.656 |
| CORO2B | POTEE | ENSP00000454783 | ENSP00000439189 | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | POTE ankyrin domain family member E | 0.727 |
| CORO2B | TLE3 | ENSP00000454783 | ENSP00000452871 | coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) | 0.755 |
| DONSON | CIB2 | ENSP00000307143 | ENSP00000258930 | downstream neighbor of SON; Essential for DNA amplification in the ovary and required for cell proliferation during development (By similarity) | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | 0.581 |
| DONSON | COPB2 | ENSP00000307143 | ENSP00000329419 | downstream neighbor of SON; Essential for DNA amplification in the ovary and required for cell proliferation during development (By similarity) | coatomer protein complex, subunit beta 2 (beta prime); The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding [...] | 0.563 |
| ITGA11 | CIB2 | ENSP00000327290 | ENSP00000258930 | integrin, alpha 11; Integrin alpha-11/beta-1 is a receptor for collagen | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | 0.803 |
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