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STRINGSTRING
TEX22 TEX22 TEX26 TEX26 CPEB4 CPEB4 CPEB2 CPEB2 FMR1 FMR1 TEX2 TEX2 FXR1 FXR1 FXR2 FXR2 CPEB3 CPEB3 NKIRAS1 NKIRAS1 TTC7B TTC7B
"TEX2" - testis expressed 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
TEX2testis expressed 2 (1134 aa)    
Predicted Functional Partners:
FMR1
fragile X mental retardation 1; Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C) (632 aa)
            score_image   0.745
FXR1
fragile X mental retardation, autosomal homolog 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity) (621 aa)
            score_image   0.745
FXR2
fragile X mental retardation, autosomal homolog 2; RNA-binding protein (673 aa)
            score_image   0.745
TEX26
testis expressed 26 (289 aa)
            score_image   0.720
TTC7B
tetratricopeptide repeat domain 7B (843 aa)
            score_image   0.718
CPEB2
cytoplasmic polyadenylation element binding protein 2; May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers (By similarity) (1034 aa)
            score_image   0.700
CPEB3
cytoplasmic polyadenylation element binding protein 3 (698 aa)
            score_image   0.700
CPEB4
cytoplasmic polyadenylation element binding protein 4 (729 aa)
            score_image   0.700
NKIRAS1
NFKB inhibitor interacting Ras-like 1; Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (192 aa)
            score_image   0.677
TEX22
testis expressed 22 (150 aa)
            score_image   0.635
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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