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ALDH4A1 ALDH4A1 GLUL GLUL GLS GLS ALDH1B1 ALDH1B1 CAD CAD ABAT ABAT INS INS ENSG00000257767 ENSG00000257767 GAD2 GAD2 ALDH7A1 ALDH7A1 SLC32A1 SLC32A1
"GAD2" - glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Catalyzes the production of GABA (585 aa)    
Predicted Functional Partners:
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
score_image     score_image score_image score_image score_image   0.985
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
      score_image score_image score_image score_image   0.969
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1; Involved in the uptake of GABA and glycine into the synaptic vesicles (525 aa)
      score_image     score_image   0.965
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) (110 aa)
            score_image   0.960
ALDH7A1
aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
      score_image score_image score_image score_image   0.952
GLS
glutaminase; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity (669 aa)
score_image     score_image   score_image score_image   0.944
GLUL
glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts (373 aa)
          score_image score_image   0.938
ALDH4A1
aldehyde dehydrogenase 4 family, member A1 (563 aa)
      score_image score_image score_image score_image   0.928
ALDH1B1
aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (517 aa)
      score_image score_image score_image score_image   0.924
ENSG00000257767
Uncharacterized protein (245 aa)
      score_image score_image score_image score_image   0.923
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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