node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C9orf171 | FAM65B | ENSP00000343290 | ENSP00000259698 | chromosome 9 open reading frame 171 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | 0.450 |
CHL1 | FAM65B | ENSP00000256509 | ENSP00000259698 | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | 0.800 |
CHL1 | MYOD1 | ENSP00000256509 | ENSP00000250003 | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | 0.414 |
CHL1 | MYOG | ENSP00000256509 | ENSP00000241651 | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | myogenin (myogenic factor 4); Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein | 0.414 |
FAM65B | C9orf171 | ENSP00000259698 | ENSP00000343290 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | chromosome 9 open reading frame 171 | 0.450 |
FAM65B | CHL1 | ENSP00000259698 | ENSP00000256509 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | 0.800 |
FAM65B | MYOD1 | ENSP00000259698 | ENSP00000250003 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | 0.493 |
FAM65B | MYOG | ENSP00000259698 | ENSP00000241651 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | myogenin (myogenic factor 4); Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein | 0.583 |
FAM65B | RHOA | ENSP00000259698 | ENSP00000400175 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | ras homolog family member A; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disor [...] | 0.623 |
FAM65B | RHOC | ENSP00000259698 | ENSP00000285735 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | ras homolog family member C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells | 0.612 |
FAM65B | TBC1D8 | ENSP00000259698 | ENSP00000366036 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.485 |
FAM65B | TBC1D8B | ENSP00000259698 | ENSP00000349781 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | TBC1 domain family, member 8B (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.485 |
FAM65B | TBC1D9 | ENSP00000259698 | ENSP00000411197 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | TBC1 domain family, member 9 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.485 |
FAM65B | TBC1D9B | ENSP00000259698 | ENSP00000349291 | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | TBC1 domain family, member 9B (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.485 |
MYOD1 | CHL1 | ENSP00000250003 | ENSP00000256509 | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | 0.414 |
MYOD1 | FAM65B | ENSP00000250003 | ENSP00000259698 | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | family with sequence similarity 65, member B; Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | 0.493 |
MYOD1 | MYOG | ENSP00000250003 | ENSP00000241651 | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | myogenin (myogenic factor 4); Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein | 0.920 |
MYOD1 | RHOA | ENSP00000250003 | ENSP00000400175 | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | ras homolog family member A; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disor [...] | 0.957 |
MYOD1 | RHOC | ENSP00000250003 | ENSP00000285735 | myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity) | ras homolog family member C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells | 0.684 |
MYOG | CHL1 | ENSP00000241651 | ENSP00000256509 | myogenin (myogenic factor 4); Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein | cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...] | 0.414 |