TMEM62 protein (Homo sapiens) - STRING network view

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TMEM62

transmembrane protein 62 (643 aa)

Predicted Functional Partners:

SH3BGRL3

0.604

COA3

0.528

PPP2R3C

0.502

ZFP37

0.494

RHBDF2

0.485

C9orf66

0.472

PLA2G15

0.467

RHBDF1

0.467

KLK8

0.421

PCCA

0.419

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C9orf66	TMEM62	ENSP00000371824	ENSP00000260403	chromosome 9 open reading frame 66	transmembrane protein 62	0.472
COA3	PPP2R3C	ENSP00000354762	ENSP00000261475	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	protein phosphatase 2, regulatory subunit B’’, gamma	0.461
COA3	RHBDF2	ENSP00000354762	ENSP00000322775	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	0.411
COA3	SH3BGRL3	ENSP00000354762	ENSP00000270792	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.543
COA3	TMEM62	ENSP00000354762	ENSP00000260403	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	transmembrane protein 62	0.528
COA3	ZFP37	ENSP00000354762	ENSP00000363344	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	zinc finger protein 37 homolog (mouse); May be involved in transcriptional regulation	0.472
KLK8	SH3BGRL3	ENSP00000375682	ENSP00000270792	kallikrein-related peptidase 8	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.409
KLK8	TMEM62	ENSP00000375682	ENSP00000260403	kallikrein-related peptidase 8	transmembrane protein 62	0.421
PCCA	TMEM62	ENSP00000365462	ENSP00000260403	propionyl CoA carboxylase, alpha polypeptide	transmembrane protein 62	0.419
PLA2G15	SH3BGRL3	ENSP00000219345	ENSP00000270792	phospholipase A2, group XV; Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.465
PLA2G15	TMEM62	ENSP00000219345	ENSP00000260403	phospholipase A2, group XV; Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity	transmembrane protein 62	0.467
PPP2R3C	COA3	ENSP00000261475	ENSP00000354762	protein phosphatase 2, regulatory subunit B’’, gamma	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	0.461
PPP2R3C	SH3BGRL3	ENSP00000261475	ENSP00000270792	protein phosphatase 2, regulatory subunit B’’, gamma	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.509
PPP2R3C	TMEM62	ENSP00000261475	ENSP00000260403	protein phosphatase 2, regulatory subunit B’’, gamma	transmembrane protein 62	0.502
PPP2R3C	ZFP37	ENSP00000261475	ENSP00000363344	protein phosphatase 2, regulatory subunit B’’, gamma	zinc finger protein 37 homolog (mouse); May be involved in transcriptional regulation	0.404
RHBDF1	SH3BGRL3	ENSP00000262316	ENSP00000270792	rhomboid 5 homolog 1 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.459
RHBDF1	TMEM62	ENSP00000262316	ENSP00000260403	rhomboid 5 homolog 1 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration	transmembrane protein 62	0.467
RHBDF2	COA3	ENSP00000322775	ENSP00000354762	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly	0.411
RHBDF2	SH3BGRL3	ENSP00000322775	ENSP00000270792	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity	0.465
RHBDF2	TMEM62	ENSP00000322775	ENSP00000260403	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	transmembrane protein 62	0.485

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