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TXNRD1 TXNRD1 ZNF99 ZNF99 LMNB1 LMNB1 TXNRD3 TXNRD3 MAP3K4 MAP3K4 ANXA10 ANXA10 MNS1 MNS1 ASRGL1 ASRGL1 STK31 STK31 GDF2 GDF2 ANLN ANLN
"MNS1" - meiosis-specific nuclear structural 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
MNS1meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) (495 aa)    
Predicted Functional Partners:
LMNB1
lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin (586 aa)
            score_image   0.860
ASRGL1
asparaginase like 1; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine (308 aa)
            score_image   0.543
TXNRD3
thioredoxin reductase 3; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity) (698 aa)
            score_image   0.506
GDF2
growth differentiation factor 2 (429 aa)
            score_image   0.483
ZNF99
zinc finger protein 99; May be involved in transcriptional regulation (1037 aa)
            score_image   0.459
ANXA10
annexin A10 (324 aa)
            score_image   0.451
MAP3K4
mitogen-activated protein kinase kinase kinase 4; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 (1608 aa)
            score_image   0.445
TXNRD1
thioredoxin reductase 1 (649 aa)
            score_image   0.443
STK31
serine/threonine kinase 31 (1019 aa)
            score_image   0.431
ANLN
anillin, actin binding protein; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (1124 aa)
            score_image   0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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