node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANLN | MNS1 | ENSP00000265748 | ENSP00000260453 | anillin, actin binding protein; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.429 |
ANXA10 | MNS1 | ENSP00000352248 | ENSP00000260453 | annexin A10 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.451 |
ASRGL1 | GDF2 | ENSP00000301776 | ENSP00000249598 | asparaginase like 1; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine | growth differentiation factor 2 | 0.547 |
ASRGL1 | MNS1 | ENSP00000301776 | ENSP00000260453 | asparaginase like 1; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.543 |
GDF2 | ASRGL1 | ENSP00000249598 | ENSP00000301776 | growth differentiation factor 2 | asparaginase like 1; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine | 0.547 |
GDF2 | MNS1 | ENSP00000249598 | ENSP00000260453 | growth differentiation factor 2 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.483 |
LMNB1 | MNS1 | ENSP00000261366 | ENSP00000260453 | lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.860 |
MAP3K4 | MNS1 | ENSP00000375986 | ENSP00000260453 | mitogen-activated protein kinase kinase kinase 4; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.445 |
MNS1 | ANLN | ENSP00000260453 | ENSP00000265748 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | anillin, actin binding protein; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression | 0.429 |
MNS1 | ANXA10 | ENSP00000260453 | ENSP00000352248 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | annexin A10 | 0.451 |
MNS1 | ASRGL1 | ENSP00000260453 | ENSP00000301776 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | asparaginase like 1; Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine | 0.543 |
MNS1 | GDF2 | ENSP00000260453 | ENSP00000249598 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | growth differentiation factor 2 | 0.483 |
MNS1 | LMNB1 | ENSP00000260453 | ENSP00000261366 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin | 0.860 |
MNS1 | MAP3K4 | ENSP00000260453 | ENSP00000375986 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | mitogen-activated protein kinase kinase kinase 4; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 | 0.445 |
MNS1 | STK31 | ENSP00000260453 | ENSP00000348132 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | serine/threonine kinase 31 | 0.431 |
MNS1 | TXNRD1 | ENSP00000260453 | ENSP00000434516 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | thioredoxin reductase 1 | 0.443 |
MNS1 | TXNRD3 | ENSP00000260453 | ENSP00000430031 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | thioredoxin reductase 3; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity) | 0.506 |
MNS1 | ZNF99 | ENSP00000260453 | ENSP00000380293 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | zinc finger protein 99; May be involved in transcriptional regulation | 0.459 |
STK31 | MNS1 | ENSP00000348132 | ENSP00000260453 | serine/threonine kinase 31 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.431 |
TXNRD1 | MNS1 | ENSP00000434516 | ENSP00000260453 | thioredoxin reductase 1 | meiosis-specific nuclear structural 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity) | 0.443 |