TTLL7 protein (Homo sapiens) - STRING network view

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TTLL7

tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity) (887 aa)

Predicted Functional Partners:

WDR64

0.722

HS6ST3

0.609

KIF1A

0.476

GPR158

0.464

TTLL12

0.449

SPATA5L1

0.441

ANKRD12

0.440

SAMD10

0.435

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD12	SAMD10	ENSP00000262126	ENSP00000358902	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	sterile alpha motif domain containing 10	0.430
ANKRD12	SPATA5L1	ENSP00000262126	ENSP00000305494	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	spermatogenesis associated 5-like 1	0.433
ANKRD12	TTLL7	ENSP00000262126	ENSP00000260505	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.440
GPR158	HS6ST3	ENSP00000365529	ENSP00000365895	G protein-coupled receptor 158; Orphan receptor	heparan sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate	0.409
GPR158	TTLL7	ENSP00000365529	ENSP00000260505	G protein-coupled receptor 158; Orphan receptor	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.464
GPR158	WDR64	ENSP00000365529	ENSP00000355510	G protein-coupled receptor 158; Orphan receptor	WD repeat domain 64	0.611
HS6ST3	GPR158	ENSP00000365895	ENSP00000365529	heparan sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate	G protein-coupled receptor 158; Orphan receptor	0.409
HS6ST3	TTLL7	ENSP00000365895	ENSP00000260505	heparan sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.609
HS6ST3	WDR64	ENSP00000365895	ENSP00000355510	heparan sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate	WD repeat domain 64	0.711
KIF1A	TTLL7	ENSP00000322791	ENSP00000260505	kinesin family member 1A	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.476
SAMD10	ANKRD12	ENSP00000358902	ENSP00000262126	sterile alpha motif domain containing 10	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	0.430
SAMD10	SPATA5L1	ENSP00000358902	ENSP00000305494	sterile alpha motif domain containing 10	spermatogenesis associated 5-like 1	0.473
SAMD10	TTLL7	ENSP00000358902	ENSP00000260505	sterile alpha motif domain containing 10	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.435
SPATA5L1	ANKRD12	ENSP00000305494	ENSP00000262126	spermatogenesis associated 5-like 1	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	0.433
SPATA5L1	SAMD10	ENSP00000305494	ENSP00000358902	spermatogenesis associated 5-like 1	sterile alpha motif domain containing 10	0.473
SPATA5L1	TTLL7	ENSP00000305494	ENSP00000260505	spermatogenesis associated 5-like 1	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.441
TTLL12	TTLL7	ENSP00000216129	ENSP00000260505	tubulin tyrosine ligase-like family, member 12	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	0.449
TTLL7	ANKRD12	ENSP00000260505	ENSP00000262126	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	ankyrin repeat domain 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation	0.440
TTLL7	GPR158	ENSP00000260505	ENSP00000365529	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	G protein-coupled receptor 158; Orphan receptor	0.464
TTLL7	HS6ST3	ENSP00000260505	ENSP00000365895	tubulin tyrosine ligase-like family, member 7; Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)	heparan sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate	0.609

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