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STRINGSTRING
BACE1 BACE1 ALDOB ALDOB KHK KHK ALDOA ALDOA HKDC1 HKDC1 ALDOC ALDOC PHPT1 PHPT1 HK3 HK3 HK1 HK1 HK2 HK2 SORD SORD
"KHK" - ketohexokinase in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
KHKketohexokinase (fructokinase) (298 aa)    
Predicted Functional Partners:
ALDOB
aldolase B, fructose-bisphosphate (364 aa)
      score_image   score_image score_image   0.960
SORD
sorbitol dehydrogenase; Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm (By similarity) (357 aa)
      score_image   score_image score_image   0.934
ALDOA
aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) (364 aa)
          score_image score_image   0.918
ALDOC
aldolase C, fructose-bisphosphate (364 aa)
          score_image score_image   0.917
HK2
hexokinase 2 (917 aa)
      score_image   score_image score_image   0.910
HK3
hexokinase 3 (white cell) (923 aa)
      score_image   score_image score_image   0.909
HK1
hexokinase 1 (921 aa)
      score_image   score_image     0.904
HKDC1
hexokinase domain containing 1 (917 aa)
      score_image   score_image     0.904
PHPT1
phosphohistidine phosphatase 1; Exhibits phosphohistidine phosphatase activity (125 aa)
          score_image     0.900
BACE1
beta-site APP-cleaving enzyme 1; Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (501 aa)
            score_image   0.804
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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