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STRINGSTRING
DPYD DPYD UMPS UMPS TMEM194B TMEM194B EPRS EPRS ACACA ACACA ACACB ACACB CAD CAD STRADA STRADA ASNSD1 ASNSD1 STRADB STRADB LARP4B LARP4B
"ASNSD1" - asparagine synthetase domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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[Homology]
Score
ASNSD1asparagine synthetase domain containing 1 (643 aa)    
Predicted Functional Partners:
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
score_image     score_image     score_image   0.645
TMEM194B
transmembrane protein 194B (417 aa)
            score_image   0.584
STRADA
STE20-related kinase adaptor alpha (431 aa)
            score_image   0.584
STRADB
STE20-related kinase adaptor beta; Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity) (418 aa)
            score_image   0.584
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
            score_image   0.552
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
            score_image   0.552
LARP4B
La ribonucleoprotein domain family, member 4B; Stimulates mRNA translation (738 aa)
            score_image   0.532
DPYD
dihydropyrimidine dehydrogenase (1025 aa)
      score_image     score_image   0.522
EPRS
glutamyl-prolyl-tRNA synthetase (1512 aa)
      score_image     score_image   0.521
UMPS
uridine monophosphate synthetase (480 aa)
      score_image     score_image   0.510
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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