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CCNY CCNY CDK9 CDK9 CDK5R2 CDK5R2 CDK15 CDK15 CKS2 CKS2 CCNF CCNF CCNA2 CCNA2 CCNA1 CCNA1 MCM3 MCM3 CKS1B CKS1B CKS1 CKS1
"CDK15" - cyclin-dependent kinase 15 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
CDK15cyclin-dependent kinase 15 (384 aa)    
Predicted Functional Partners:
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39); Activator of CDK5/TPKII (367 aa)
        score_image   score_image   0.870
CKS1
CDC28 protein kinase regulatory subunit 1B; CDC28 protein kinase regulatory subunit 1B, isoform CRA_b; cDNA, FLJ92030, Homo sapiens CDC28 protein kinase regulatory subunit 1B (CKS1B),mRNA ; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (79 aa)
      score_image score_image   score_image   0.853
CKS2
CDC28 protein kinase regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (79 aa)
      score_image score_image   score_image   0.853
CKS1B
CDC28 protein kinase regulatory subunit 1B; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (79 aa)
      score_image score_image   score_image   0.853
CCNY
cyclin Y (341 aa)
        score_image   score_image   0.852
CCNA2
cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions (432 aa)
  score_image   score_image score_image   score_image   0.850
CCNF
cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication (786 aa)
      score_image score_image   score_image   0.845
CCNA1
cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells (465 aa)
      score_image score_image   score_image   0.845
CDK9
cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytok [...] (372 aa)
    score_image   score_image   score_image score_image 0.845
MCM3
minichromosome maintenance complex component 3; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute dif [...] (808 aa)
      score_image score_image   score_image   0.822
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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