| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C9orf174 | CABLES1 | ENSP00000364348 | ENSP00000256925 | chromosome 9 open reading frame 174 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.660 |
| C9orf174 | CDK17 | ENSP00000364348 | ENSP00000261211 | chromosome 9 open reading frame 174 | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.860 |
| C9orf174 | TDRD7 | ENSP00000364348 | ENSP00000347444 | chromosome 9 open reading frame 174 | tudor domain containing 7 | 0.867 |
| CABLES1 | C9orf174 | ENSP00000256925 | ENSP00000364348 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | chromosome 9 open reading frame 174 | 0.660 |
| CABLES1 | CCNA1 | ENSP00000256925 | ENSP00000255465 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | 0.613 |
| CABLES1 | CDK17 | ENSP00000256925 | ENSP00000261211 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.952 |
| CABLES1 | TDRD7 | ENSP00000256925 | ENSP00000347444 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | tudor domain containing 7 | 0.982 |
| CCNA1 | CABLES1 | ENSP00000255465 | ENSP00000256925 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.613 |
| CCNA1 | CDK17 | ENSP00000255465 | ENSP00000261211 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.847 |
| CCNA1 | CKS1 | ENSP00000255465 | ENSP00000471505 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | CDC28 protein kinase regulatory subunit 1B; CDC28 protein kinase regulatory subunit 1B, isoform CRA_b; cDNA, FLJ92030, Homo sapiens CDC28 protein kinase regulatory subunit 1B (CKS1B),mRNA ; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.835 |
| CCNA1 | CKS1B | ENSP00000255465 | ENSP00000311083 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | CDC28 protein kinase regulatory subunit 1B; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.949 |
| CCNA1 | CKS2 | ENSP00000255465 | ENSP00000364976 | cyclin A1; May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells | CDC28 protein kinase regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.953 |
| CCNA2 | CDK17 | ENSP00000274026 | ENSP00000261211 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.849 |
| CCNA2 | CKS1 | ENSP00000274026 | ENSP00000471505 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | CDC28 protein kinase regulatory subunit 1B; CDC28 protein kinase regulatory subunit 1B, isoform CRA_b; cDNA, FLJ92030, Homo sapiens CDC28 protein kinase regulatory subunit 1B (CKS1B),mRNA ; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.970 |
| CCNA2 | CKS1B | ENSP00000274026 | ENSP00000311083 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | CDC28 protein kinase regulatory subunit 1B; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.992 |
| CCNA2 | CKS2 | ENSP00000274026 | ENSP00000364976 | cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions | CDC28 protein kinase regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.987 |
| CCNF | CDK17 | ENSP00000380256 | ENSP00000261211 | cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication | cyclin-dependent kinase 17; May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity) | 0.845 |
| CCNF | CKS1 | ENSP00000380256 | ENSP00000471505 | cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication | CDC28 protein kinase regulatory subunit 1B; CDC28 protein kinase regulatory subunit 1B, isoform CRA_b; cDNA, FLJ92030, Homo sapiens CDC28 protein kinase regulatory subunit 1B (CKS1B),mRNA ; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.898 |
| CCNF | CKS1B | ENSP00000380256 | ENSP00000311083 | cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication | CDC28 protein kinase regulatory subunit 1B; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.895 |
| CCNF | CKS2 | ENSP00000380256 | ENSP00000364976 | cyclin F; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication | CDC28 protein kinase regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function | 0.892 |
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